SCHEMBL21534752

SCHEMBL21534752

CC1(C)c2ccccc2-c2ccc(-c3ccco3)cc21

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TDP2 O95551 2/20 0.46
LPL P06858 1/20 0.42
LIPG Q9Y5X9 1/20 0.42
PGR P06401 1/20 0.40
TAAR1 Q96RJ0 2/20 0.40
PIK3R1 P27986 4/20 0.39
PIK3CA P42336 4/20 0.39
PDK2 Q15119 1/20 0.39
ALDH1A1 P00352 1/20 0.38
HPGD P15428 1/20 0.38
PRMT6 Q96LA8 1/20 0.38
ERN1 O75460 1/20 0.38
HDAC2 Q92769 1/20 0.37
SMARCA2 P51531 1/20 0.37
PBRM1 Q86U86 1/20 0.37
FLT3 P36888 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21534753 0.91 TDP2 (0.46) TDP2LPLLIPGPGRTAAR1
SCHEMBL21868075 0.87 TDP2 (0.40) TDP2LPLLIPGPGRTAAR1
SCHEMBL27023020 0.85 PDK2 (0.34) TDP2LPLLIPGPIK3R1PIK3CA
SCHEMBL24309532 0.84 TDP2 (0.48) TDP2LPLLIPGPGRTAAR1
SCHEMBL20931914 0.84 PGR (0.36) TDP2LPLLIPGPGRTAAR1
SCHEMBL21868301 0.84 TDP2 (0.43) TDP2LPLLIPGPGRTAAR1
SCHEMBL24293169 0.82 PRMT6 (0.38) TDP2LPLLIPGTAAR1PIK3R1
SCHEMBL1649136 0.81 PDK2 (0.47) PDK2
SCHEMBL20932456 0.80 PRMT6 (0.34) TDP2LPLLIPGPGRTAAR1
SCHEMBL30009790 0.79 PDK2 (0.50) PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11289654-B2 Polymers containing furanyl crosslinkable groups and uses thereof GUANGZHOU CHINARAY OPTOELECTRONIC MATERIALS LTD. (CN) 2022-03-29 US disclosed
EP-3560917-A1 POLYMER CONTAINING FURAN CROSSLINKING GROUP AND USE THEREOF Guangzhou Chinaray Optoelectronic Materials Ltd. (CN) 2019-10-30 EP disclosed