Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 6/20 | 0.38 |
| ▸ | CHKA | P35790 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 3/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21534963 | 0.99 | KDM1A (0.38) | KDM1ACHKAMCHR1OPRM1OPRK1 | |
| SCHEMBL21535094 | 0.92 | KDM1A (0.35) | KDM1AOPRM1OPRK1ACHEMAOB | |
| SCHEMBL21534901 | 0.91 | ALDH1A1 (0.35) | KDM1ACHKAACHE | |
| SCHEMBL21534885 | 0.91 | KDM1A (0.34) | KDM1ACHKAACHEMAOBMAOA | |
| SCHEMBL21534872 | 0.89 | CHRM4 (0.35) | KDM1ACHKAOPRM1OPRK1MAOB | |
| SCHEMBL21535062 | 0.88 | OPRM1 (0.36) | KDM1ACHKAOPRM1OPRK1MAOB | |
| SCHEMBL21534621 | 0.88 | MAOB (0.39) | MAOBMAOA | |
| SCHEMBL21534972 | 0.87 | MAOB (0.39) | MAOBMAOA | |
| SCHEMBL21534897 | 0.87 | MCHR1 (0.39) | KDM1ACHKAMCHR1OPRM1OPRK1 | |
| SCHEMBL21534891 | 0.86 | OPRM1 (0.40) | MCHR1OPRM1OPRK1MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2858986-B1 | PIPERIDINE DERIVATIVES AS GPR119 AGONISTS | CHONG KUN DANG PHARMACEUTICAL CORP (KR) | 2019-10-30 | — | — | EP | disclosed |