Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.36 |
| ▸ | MTOR | P42345 | 2/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.34 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15539058 | 0.88 | CNR2 (0.39) | GPR119PIK3CAPDK1PDK2PDK3 | |
| SCHEMBL15539062 | 0.88 | CNR2 (0.39) | GPR119PIK3CAPDK1PDK2PDK3 | |
| SCHEMBL20053643 | 0.85 | GPR119 (0.43) | GPR119PIK3CAMTORPDK1PDK2 | |
| SCHEMBL15538258 | 0.83 | GPR119 (0.43) | GPR119PDK1PDK2PDK3PDK4 | |
| SCHEMBL15538905 | 0.82 | PIK3CA (0.41) | GPR119PIK3CAMTORPDK1PDK2 | |
| SCHEMBL15538907 | 0.82 | PIK3CA (0.41) | GPR119PIK3CAMTORPDK1PDK2 | |
| SCHEMBL15537883 | 0.81 | PIK3CA (0.43) | GPR119PIK3CAMTORLRRK2PDK2 | |
| SCHEMBL15537881 | 0.81 | PIK3CA (0.43) | GPR119PIK3CAMTORLRRK2PDK2 | |
| SCHEMBL15537774 | 0.81 | PIK3CA (0.44) | GPR119PIK3CAMTORHCRTR1HCRTR2 | |
| SCHEMBL15537777 | 0.81 | PIK3CA (0.44) | GPR119PIK3CAMTORHCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2858986-B1 | PIPERIDINE DERIVATIVES AS GPR119 AGONISTS | CHONG KUN DANG PHARMACEUTICAL CORP (KR) | 2019-10-30 | — | — | EP | disclosed |