SCHEMBL15538907

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15538905	1.00	PIK3CA (0.41)	PIK3CAMTORALOX5APFEN1GPR119
	SCHEMBL20053643	0.92	GPR119 (0.43)	PIK3CAMTORGPR119HCRTR1HCRTR2
	SCHEMBL15538518	0.89	ALOX5AP (0.46)	PIK3CAMTORALOX5APFEN1GPR119
	SCHEMBL15538520	0.89	ALOX5AP (0.46)	PIK3CAMTORALOX5APFEN1GPR119
	SCHEMBL15539321	0.89	ALOX5AP (0.46)	PIK3CAMTORALOX5APFEN1GPR119
	SCHEMBL15539856	0.89	PIK3CA (0.44)	PIK3CAMTORALOX5APFEN1GPR119
	SCHEMBL15538166	0.89	PIK3CA (0.44)	PIK3CAMTORALOX5APFEN1GPR119
	SCHEMBL15538162	0.89	PIK3CA (0.44)	PIK3CAMTORALOX5APFEN1GPR119
	SCHEMBL15538352	0.88	GRM3 (0.40)	GPR119KMT2A
	SCHEMBL15538353	0.88	GRM3 (0.40)	GPR119KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.