Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKE | Q14164 | 1/20 | 0.36 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | WNT1 | P04628 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21535147 | 0.91 | IKBKE (0.38) | IKBKETBK1HRH3HTR2AHTR2C | |
| SCHEMBL21042686 | 0.86 | IKBKE (0.39) | IKBKETBK1HRH3HTR2AHTR2C | |
| SCHEMBL21534693 | 0.85 | HTR2A (0.35) | IKBKETBK1HRH3HTR2AHTR2C | |
| SCHEMBL21042908 | 0.85 | IKBKE (0.38) | IKBKETBK1HTR2AHTR2CGPR119 | |
| SCHEMBL21534996 | 0.83 | KDM1A (0.36) | IKBKETBK1HTR2AHTR2C | |
| SCHEMBL21534859 | 0.81 | DYRK1A (0.35) | HRH3GPR119WNT1DYRK1A | |
| SCHEMBL21534682 | 0.81 | HTR2A (0.37) | IKBKETBK1HTR2AHTR2CITGB3 | |
| SCHEMBL21535067 | 0.80 | OPRM1 (0.36) | HRH3HTR2AHTR2CWNT1DYRK1A | |
| SCHEMBL21534894 | 0.80 | HTR2A (0.35) | HTR2AHTR2CWNT1DYRK1A | |
| SCHEMBL21535065 | 0.79 | OPRM1 (0.39) | HTR2AHTR2CWNT1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2858986-B1 | PIPERIDINE DERIVATIVES AS GPR119 AGONISTS | CHONG KUN DANG PHARMACEUTICAL CORP (KR) | 2019-10-30 | — | — | EP | disclosed |