Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKE | Q14164 | 1/20 | 0.38 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 9/20 | 0.33 |
| ▸ | WNT1 | P04628 | 3/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 4/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 3/20 | 0.32 |
| ▸ | MAOA | P21397 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21042686 | 0.93 | IKBKE (0.39) | IKBKETBK1HTR2AHTR2CCHRM4 | |
| SCHEMBL21535147 | 0.89 | IKBKE (0.38) | IKBKETBK1HTR2AHTR2CCHRM4 | |
| SCHEMBL21535149 | 0.85 | IKBKE (0.36) | IKBKETBK1HTR2AHTR2CDYRK1A | |
| SCHEMBL21534983 | 0.81 | HTR2A (0.40) | IKBKETBK1HTR2AHTR2CCHRM4 | |
| SCHEMBL21534682 | 0.81 | HTR2A (0.37) | IKBKETBK1HTR2AHTR2CCHRM4 | |
| SCHEMBL21534693 | 0.79 | HTR2A (0.35) | IKBKETBK1HTR2AHTR2CCHRM4 | |
| SCHEMBL21534996 | 0.78 | KDM1A (0.36) | IKBKETBK1HTR2AHTR2C | |
| SCHEMBL21043233 | 0.76 | HTR2A (0.41) | IKBKETBK1HTR2AHTR2CCHRM4 | |
| SCHEMBL21535065 | 0.76 | OPRM1 (0.39) | HTR2AHTR2CCHRM4DYRK1AWNT1 | |
| SCHEMBL21534641 | 0.75 | OPRM1 (0.40) | HTR2AHTR2CCHRM4DYRK1AWNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3074384-B1 | AMIDE DERIVATIVES FOR GPR119 AGONIST | CHONG KUN DANG PHARMACEUTICAL CORP (KR) | 2019-05-22 | — | — | EP | disclosed |