Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 17/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.35 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.35 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31260036 | 0.88 | CYP11B1 (0.47) | BMPR1BACVRL1ACVR1CYP11B1CYP11B2 | |
| SCHEMBL14789849 | 0.88 | CYP11B1 (0.47) | BMPR1BACVRL1ACVR1CYP11B1CYP11B2 | |
| SCHEMBL22004587 | 0.77 | CYP11B2 (0.41) | CYP11B1CYP11B2 | |
| SCHEMBL22005290 | 0.77 | CYP11B2 (0.51) | CYP11B1CYP11B2 | |
| SCHEMBL22004749 | 0.76 | CYP11B2 (0.39) | CYP11B1CYP11B2 | |
| SCHEMBL21535156 | 0.74 | CYP11B2 (0.40) | CYP11B1CYP11B2 | |
| SCHEMBL22004705 | 0.74 | CYP11B2 (0.46) | CYP11B1CYP11B2 | |
| SCHEMBL21535345 | 0.69 | MAPK1 (0.39) | CYP11B1CYP11B2 | |
| SCHEMBL14789859 | 0.68 | CYP11B1 (0.51) | CYP11B1CYP11B2 | |
| SCHEMBL31259986 | 0.68 | CYP11B1 (0.51) | CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2755963-B1 | NEW DIHYDROQUINOLINE-2-ONE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2019-10-30 | — | — | EP | disclosed |