SCHEMBL2153565

SCHEMBL2153565

O=C(Oc1c(F)c(F)cc(F)c1F)Oc1c(F)c(F)cc(F)c1F

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.44
CA2 P00918 3/20 0.44
CA4 P22748 2/20 0.44
CES2 O00748 3/20 0.42
CES1 P23141 3/20 0.42
MAPT P10636 3/20 0.39
KDM4E B2RXH2 3/20 0.39
ALDH1A1 P00352 3/20 0.39
HTT P42858 2/20 0.39
MAPK1 P28482 2/20 0.35
CA12 O43570 1/20 0.34
CA7 P43166 1/20 0.34
CA13 Q8N1Q1 1/20 0.34
MAOB P27338 1/20 0.33
ALPL P05186 1/20 0.33
CYP4F2 P78329 1/20 0.32
CYP4A11 Q02928 1/20 0.32
LMNA P02545 1/20 0.31
RAB9A P51151 1/20 0.31
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18697369 0.85 CA1 (0.44) CA1CA2CA4CES2CES1
SCHEMBL1994881 0.83 CA1 (0.43) CA1CA2CA4CES2CES1
SCHEMBL26770524 0.83 CA1 (0.43) CA1CA2CA4CES2CES1
SCHEMBL15033733 0.82 MAPT (0.36) CA1CA2CA4CES2CES1
SCHEMBL27110084 0.81 CA1 (0.41) CA1CA2CA4CES2CES1
SCHEMBL17740107 0.81 CA1 (0.41) CA1CA2CA4CES2CES1
SCHEMBL14563139 0.79 CES2 (0.43) CA1CA2CA4CES2CES1
SCHEMBL22381463 0.79 CA1 (0.40) CA1CA2CA4CES2CES1
SCHEMBL15763915 0.79 MAPT (0.43) CA1CA2CA4CES2CES1
SCHEMBL29319716 0.79 CES2 (0.34) CA1CA2CA4CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3626701-B1 FLUORINATED CARBONATE DERIVATIVE PRODUCTION METHOD UNIV KOBE NAT UNIV CORP (JP) 2024-07-17 EP disclosed
US-11167259-B2 Fluorinated carbonate derivative production method NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) 2021-11-09 US disclosed
US-11167259-B2 Fluorinated carbonate derivative production method NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) 2021-11-09 US disclosed
US-20200122114-A1 FLUORINATED CARBONATE DERIVATIVE PRODUCTION METHOD NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) 2020-04-23 US disclosed
US-20200122114-A1 FLUORINATED CARBONATE DERIVATIVE PRODUCTION METHOD NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) 2020-04-23 US disclosed
EP-3626701-A1 FLUORINATED CARBONATE DERIVATIVE PRODUCTION METHOD National University Corporation Kobe University (JP) 2020-03-25 EP disclosed
CN-110719904-A Process for producing fluorinated carbonate derivative 国立大学法人神户大学 2020-01-21 CN disclosed
US-10377847-B2 Strong reversible hydrogels SUPRAPOLIX B.V. (NL) 2019-08-13 US disclosed
EP-2343342-B1 STRONG REVERSIBLE HYDROGELS SUPRAPOLIX BV (NL) 2015-09-16 EP disclosed
US-20140128482-A1 STRONG REVERSIBLE HYDROGELS SUPRAPOLIX B.V. (NL) 2014-05-08 US disclosed
US-8628789-B2 Strong reversible hydrogels SUPRAPOLIX, B.V. (NL) 2014-01-14 US disclosed
EP-2343342-A1 Strong reversible hydrogels SupraPolix B.V. (NL) 2011-07-13 EP disclosed
EP-1972661-B1 Strong reversible hydrogels SUPRAPOLIX BV (NL) 2011-07-06 EP disclosed
US-20080260795-A1 STRONG REVERSIBLE HYDROGELS SUPRAPOLIX B.V. 2008-10-23 US disclosed
EP-1972661-A1 Strong reversible hydrogels SupraPolix B.V. (NL) 2008-09-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10377847-B2 Strong reversible hydrogels HSPA4L, H1-4, CD44 CA1 4260/4885CA2 4259/4885CA4 3759/4885
US-11167259-B2 Fluorinated carbonate derivative production method CA4, CA3, CA14 CA1 9/4885CA2 5/4885CA4 1/4885
US-20200122114-A1 FLUORINATED CARBONATE DERIVATIVE PRODUCTION METHOD CA4, CA3, CA14 CA1 9/4885CA2 5/4885CA4 1/4885
US-20080260795-A1 STRONG REVERSIBLE HYDROGELS HSPA4L, H1-4, CD44 CA1 4260/4885CA2 4259/4885CA4 3759/4885
US-20140128482-A1 STRONG REVERSIBLE HYDROGELS HSPA4L, H1-4, CD44 CA1 4260/4885CA2 4259/4885CA4 3759/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.