Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | SCN4A | P35499 | 2/20 | 0.51 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.51 |
| ▸ | GMNN | O75496 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2665688 | 0.87 | NPC1 (0.68) | NPC1RAB9ASMN1; SMN2HSD17B10TP53 | |
| SCHEMBL14806544 | 0.85 | PDE10A (0.49) | POLBNPC1RAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL31132377 | 0.81 | RAB9A (0.77) | NPC1RAB9ASMN1; SMN2HSD17B10TP53 | |
| SCHEMBL9184354 | 0.81 | NPC1 (0.51) | NPC1RAB9ASMN1; SMN2HSD17B10TP53 | |
| SCHEMBL3463902 | 0.81 | NPC1 (0.51) | NPC1RAB9ASMN1; SMN2HSD17B10TP53 | |
| SCHEMBL480862 | 0.81 | RAB9A (0.77) | NPC1RAB9ASMN1; SMN2HSD17B10TP53 | |
| SCHEMBL2749069 | 0.81 | NPC1 (0.51) | NPC1RAB9ASMN1; SMN2HSD17B10TP53 | |
| SCHEMBL31276816 | 0.80 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2HSD17B10TP53 | |
| SCHEMBL95067 | 0.80 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2HSD17B10TP53 | |
| SCHEMBL1133234 | 0.79 | POLB (0.62) | POLBNPC1RAB9ASMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10463661-B2 | Anthelmintic compounds | Boehringer Ingelheim Animal Health USA Inc. (US) | 2019-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10463661-B2 | Anthelmintic compounds | HRH4, QTRT1, Q6ZSR9 | POLB 3477/4885NPC1 2700/4885RAB9A 1624/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.