Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | SCN4A | P35499 | 2/20 | 0.51 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.51 |
| ▸ | GMNN | O75496 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1748078 | 0.87 | NPC1 (0.68) | NPC1RAB9ASCN4ASCN9AGMNN | |
| SCHEMBL31132377 | 0.81 | RAB9A (0.77) | NPC1RAB9ASCN4ASCN9AGMNN | |
| SCHEMBL21536795 | 0.81 | POLB (0.52) | NPC1RAB9ASCN4ASCN9AGMNN | |
| SCHEMBL2749069 | 0.81 | NPC1 (0.51) | NPC1RAB9ASCN4ASCN9AGMNN | |
| SCHEMBL480862 | 0.81 | RAB9A (0.77) | NPC1RAB9ASCN4ASCN9AGMNN | |
| SCHEMBL9184354 | 0.81 | NPC1 (0.51) | NPC1RAB9ASCN4ASCN9AGMNN | |
| SCHEMBL779852 | 0.78 | NPC1 (0.54) | NPC1RAB9ALMNATP53CYP1A2 | |
| SCHEMBL3639457 | 0.76 | PPARA (0.48) | NPC1RAB9ASCN4ASCN9AGMNN | |
| SCHEMBL15516907 | 0.75 | NPC1 (0.46) | NPC1RAB9ASCN4ASCN9AGMNN | |
| SCHEMBL777758 | 0.75 | DYRK1A (0.52) | SCN4ASMN1; SMN2KMT2ADYRK1AIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010010435-A2 | FUSED OXAZOLE AND THIAZOLE DERIVATIVES AS TRPMS MODULATORS | GLENMARK PHARMACEUTICAL S.A. (CH) | 2010-01-28 | — | — | WO | disclosed |
| EP-0060426-B1 | N-(2,2,2-TRIFLUOROETHYL)-N-ALKYL-AZOLYLOXYACETIC-ACID AMIDES, THEIR PREPARATION AND USE AS HERBICIDES AND INTERMEDIATES FOR THEIR PREPARATION | BAYER AG (DE) | 1986-04-23 | — | — | EP | disclosed |
| US-4465504-A | Herbicidally active novel N-(2,2,2-trifluoroethyl)-N-alkyl-azolyloxyacetic acid amides and intermediates therefor | BAYER AKTIENGESELLSCHAFT (DE) | 1984-08-14 | — | — | US | disclosed |
| US-4455428-A | HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1984-06-19 | — | — | US | disclosed |
| EP-0029171-B1 | AZOLYLOXY-CARBOXYLIC ACID N-OXY-AMIDES, PROCESS AND INTERMEDIATES FOR THEIR PREPARATION, THEIR USE, HERBICIDES CONTAINING THEM AND THEIR PREPARATION | BAYER AG (DE) | 1984-03-21 | — | — | EP | disclosed |
| US-4408055-A | HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1983-10-04 | — | — | US | disclosed |
| EP-0081730-A1 | Process for the preparation of hetaryloxyacetamides | BAYER AG (DE) | 1983-06-22 | — | — | EP | disclosed |
| EP-0060426-A2 | N-(2,2,2-trifluoroethyl)-N-alkyl-azolyloxyacetic-acid amides, their preparation and use as herbicides and intermediates for their preparation | BAYER AG (DE) | 1982-09-22 | — | — | EP | disclosed |