Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.37 |
| ▸ | APP | P05067 | 2/20 | 0.35 |
| ▸ | TERT | O14746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4156637 | 0.77 | ACHE (0.35) | ACHE | |
| SCHEMBL4391221 | 0.77 | ALDH1A1 (0.67) | ALDH1A1TSHRHSD17B10ALOX15NOTUM | |
| SCHEMBL30602821 | 0.70 | ALDH1A1 (0.58) | ALDH1A1TSHRHSD17B10ALOX15NOTUM | |
| SCHEMBL23954385 | 0.70 | ALDH1A1 (0.52) | ALDH1A1TSHRHSD17B10ALOX15NOTUM | |
| SCHEMBL30704068 | 0.70 | ALDH1A1 (0.52) | ALDH1A1TSHRHSD17B10ALOX15NOTUM | |
| SCHEMBL2083140 | 0.70 | ALDH1A1 (0.52) | ALDH1A1TSHRHSD17B10ALOX15NOTUM | |
| SCHEMBL30704069 | 0.70 | ALDH1A1 (0.52) | ALDH1A1TSHRHSD17B10ALOX15NOTUM | |
| SCHEMBL1556125 | 0.69 | — | — | |
| SCHEMBL1920861 | 0.69 | ALDH1A1 (0.56) | ALDH1A1TSHRHSD17B10ALOX15NOTUM | |
| SCHEMBL12879 | 0.69 | ALDH1A1 (0.56) | ALDH1A1TSHRHSD17B10ALOX15NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2519548-A1 | AMINOSILANE INITIATORS AND FUNCTIONALIZED POLYMERS PREPARED THEREFROM | Bridgestone Corporation (JP) | 2012-11-07 | — | — | EP | disclosed |
| WO-2011082277-A1 | AMINOSILANE INITIATORS AND FUNCTIONALIZED POLYMERS PREPARED THEREFROM | BRIDGESTONE CORPORATION (JP) | 2011-07-07 | — | — | WO | disclosed |