Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21539942 | 0.91 | MDM2 (0.41) | MAPTMDM2ALDH1A1HTTNPSR1 | |
| SCHEMBL21539944 | 0.84 | MDM2 (0.42) | MAPTMDM2ALDH1A1HTTNPSR1 | |
| SCHEMBL17366169 | 0.74 | MDM2 (0.58) | MAPTMDM2ALDH1A1HTTNPSR1 | |
| SCHEMBL30121977 | 0.68 | MDM2 (0.64) | MAPTMDM2ALDH1A1HTTNPSR1 | |
| SCHEMBL20100175 | 0.67 | MDM2 (0.44) | MAPTMDM2ALDH1A1TP53 | |
| SCHEMBL2643902 | 0.63 | MAPT (0.50) | MAPTMDM2ALDH1A1HPGDCASP3 | |
| SCHEMBL17366155 | 0.63 | CYP2C9 (0.56) | MAPTMDM2 | |
| SCHEMBL17366151 | 0.63 | MDM2 (0.58) | MAPTMDM2ALDH1A1HTTNPSR1 | |
| SCHEMBL17366174 | 0.63 | MDM2 (0.58) | MAPTMDM2ALDH1A1HTTNPSR1 | |
| SCHEMBL17366170 | 0.63 | MDM2 (0.64) | MAPTMDM2ALDH1A1HTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2960233-B1 | NEW THERAPEUTIC AGENTS | CANCER RESEARCH TECH LTD (GB) | 2019-10-30 | — | — | EP | disclosed |