Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 6/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4095527 | 0.80 | HRH1 (0.49) | MAPK14HRH1CHRM2HTR1ACHRM1 | |
| SCHEMBL11992050 | 0.79 | PTAFR (0.43) | MAPK14HRH1CHRM2HTR1ACHRM1 | |
| SCHEMBL13421144 | 0.77 | HRH1 (0.41) | MAPK14HRH1CHRM2HTR1ACHRM1 | |
| SCHEMBL14255009 | 0.73 | CES1 (0.52) | MAPK14LMNAKMT2AKDM4EALDH1A1 | |
| SCHEMBL11992052 | 0.72 | CCR1 (0.40) | MAPK14HRH1CHRM2HTR1ACHRM1 | |
| SCHEMBL12797068 | 0.72 | KDM4E (0.49) | LMNADRD4HRH4KDM4EALDH1A1 | |
| SCHEMBL4912110 | 0.72 | TSHR (0.43) | HRH1CHRM2HTR1ACHRM1DRD2 | |
| SCHEMBL12696414 | 0.72 | CASP1 (0.46) | FNTAFNTBCASP1HSD17B10 | |
| SCHEMBL595017 | 0.70 | HRH1 (0.40) | MAPK14HRH1CHRM2HTR1ACHRM1 | |
| SCHEMBL29993467 | 0.69 | MAPT (0.50) | MAPK14HRH1CHRM2HTR1ACHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3406597-B1 | CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | SAMSUNG DISPLAY CO LTD (KR) | 2019-10-30 | — | — | EP | disclosed |