SCHEMBL595017

SCHEMBL595017

c1cnc2c(c1)CCc1cncnc1-2

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH1 P35367 5/20 0.40
CHRM2 P08172 2/20 0.40
HTR1A P08908 2/20 0.40
CHRM1 P11229 2/20 0.40
DRD2 P14416 2/20 0.40
HTR2A P28223 2/20 0.40
HTR2C P28335 2/20 0.40
ADRA1A P35348 2/20 0.40
OPRK1 P41145 2/20 0.40
HTR2B P41595 2/20 0.40
KCNH2 Q12809 2/20 0.40
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
LMNA P02545 1/20 0.35
ADRB2 P07550 1/20 0.35
CHRM4 P08173 1/20 0.35
ABCB1 P08183 1/20 0.35
CHRM5 P08912 1/20 0.35
ADRA2A P08913 1/20 0.35
ADRA2B P18089 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17264307 0.85 GABRG2 (0.41) MEN1KMT2AKDM4EALDH1A1GABRG2
SCHEMBL4095527 0.83 HRH1 (0.49) HRH1CHRM2HTR1ACHRM1DRD2
SCHEMBL29811175 0.77 KDM4E (0.54) LMNAKDM4EALDH1A1POLBGABRG2
SCHEMBL4400157 0.77 KDM4E (0.54) LMNAKDM4EALDH1A1POLBGABRG2
SCHEMBL18462131 0.76 SIGMAR1 (0.44) HRH1CHRM2HTR1ACHRM1DRD2
SCHEMBL4912110 0.74 TSHR (0.43) HRH1CHRM2HTR1ACHRM1DRD2
SCHEMBL15750969 0.73 GABRG2 (0.33) GABRG2GABRB3GABRA5
SCHEMBL13421144 0.72 HRH1 (0.41) HRH1CHRM2HTR1ACHRM1DRD2
SCHEMBL21539953 0.70 MAPK14 (0.39) HRH1CHRM2HTR1ACHRM1DRD2
SCHEMBL11992050 0.70 PTAFR (0.43) HRH1CHRM2HTR1ACHRM1DRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8329898-B2 Pyrido[3,2-h]quinazolines and/or 5,6-dihydro derivatives thereof, a method for the production thereof and doped organic semiconductor material containing these NOVALED AG (DE) 2012-12-11 US claimed
US-20120041197-A1 Pyrido[3,2-h]quinazolines and/or 5,6-dihydro Derivatives Thereof, a Method for the Production Thereof and Doped Organic Semiconductor Material Containing These NOVALED AG (DE) 2012-02-16 US claimed
US-20110046374-A1 Pyrido[3,2-h]quinazolines and/or 5,6-dihydro Derivatives Thereof, a Method for the Production Thereof and Doped Organic Semiconductor Material Containing These NOVALED AG (DE) 2011-02-24 US claimed
US-7807687-B2 Pyrido[3,2-h]quinazolines and/or 5,6-dihydro derivatives thereof, a method for the production thereof and doped organic semiconductor material containing these NOVALED AG (DE) 2010-10-05 US claimed
EP-1970371-B1 Pyrido(3,2-h)chinazolins and/or 5,6-Dihydro derivatives thereof, method for their manufacture and endowed organic semiconductor material containing them NOVALED AG (DE) 2010-08-25 EP claimed
US-20080227979-A1 Pyrido[3,2-h]quinazolines and/or 5,6-dihydro derivatives thereof, a method for the production thereof and doped organic semiconductor material containing these NOVALED AG (DE) 2008-09-18 US claimed
EP-1970371-A1 Pyrido(3,2-h)chinazolins and/or 5,6-Dihydro derivatives thereof, method for their manufacture and endowed organic semiconductor material containing them Novaled AG (DE) 2008-09-17 EP claimed
US-11673100-B2 Systems and methods for integrated solar photodialysis THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-06-13 US disclosed
US-11673100-B2 Systems and methods for integrated solar photodialysis THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-06-13 US disclosed
US-11318424-B2 Light-driven ion-pumping membrane systems THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-05-03 US disclosed
US-20190217255-A1 SYSTEMS AND METHODS FOR INTEGRATED SOLAR PHOTODIALYSIS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2019-07-18 US disclosed
US-20180065095-A1 LIGHT-DRIVEN ION-PUMPING MEMBRANE SYSTEMS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2018-03-08 US disclosed
US-20180065095-A1 LIGHT-DRIVEN ION-PUMPING MEMBRANE SYSTEMS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2018-03-08 US disclosed
US-20120041197-A1 Pyrido[3,2-h]quinazolines and/or 5,6-dihydro Derivatives Thereof, a Method for the Production Thereof and Doped Organic Semiconductor Material Containing These NOVALED AG (DE) 2012-02-16 US disclosed
US-8115003-B2 Pyrido[3,2-h]quinazolines and/or 5,6-dihydro derivatives thereof, a method for the production thereof and doped organic semiconductor material containing these NOVALED AG (DE) 2012-02-14 US disclosed
US-20110046374-A1 Pyrido[3,2-h]quinazolines and/or 5,6-dihydro Derivatives Thereof, a Method for the Production Thereof and Doped Organic Semiconductor Material Containing These NOVALED AG (DE) 2011-02-24 US disclosed
US-7807687-B2 Pyrido[3,2-h]quinazolines and/or 5,6-dihydro derivatives thereof, a method for the production thereof and doped organic semiconductor material containing these NOVALED AG (DE) 2010-10-05 US disclosed
EP-1970371-B1 Pyrido(3,2-h)chinazolins and/or 5,6-Dihydro derivatives thereof, method for their manufacture and endowed organic semiconductor material containing them NOVALED AG (DE) 2010-08-25 EP disclosed
US-20080227979-A1 Pyrido[3,2-h]quinazolines and/or 5,6-dihydro derivatives thereof, a method for the production thereof and doped organic semiconductor material containing these NOVALED AG (DE) 2008-09-18 US disclosed
EP-1970371-A1 Pyrido(3,2-h)chinazolins and/or 5,6-Dihydro derivatives thereof, method for their manufacture and endowed organic semiconductor material containing them Novaled AG (DE) 2008-09-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120041197-A1 Pyrido[3,2-h]quinazolines and/or 5,6-dihydro Derivatives Thereof, a Method for the Production Thereof and Doped Organic Semiconductor Material Containing These PDXK, PNPO, QDPR HRH1 100/4885CHRM2 1072/4885HTR1A 723/4885
US-20080227979-A1 Pyrido[3,2-h]quinazolines and/or 5,6-dihydro derivatives thereof, a method for the production thereof and doped organic semiconductor material containing these PDXK, PNPO, QDPR HRH1 100/4885CHRM2 1072/4885HTR1A 723/4885
US-20110046374-A1 Pyrido[3,2-h]quinazolines and/or 5,6-dihydro Derivatives Thereof, a Method for the Production Thereof and Doped Organic Semiconductor Material Containing These PDXK, PNPO, QDPR HRH1 100/4885CHRM2 1072/4885HTR1A 723/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.