Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | FKBP1A | P62942 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21540140 | 0.85 | KMT2A (0.59) | SIGMAR1KMT2AMEN1POLBFKBP1A | |
| SCHEMBL21594744 | 0.85 | KMT2A (0.59) | SIGMAR1KMT2AMEN1POLBFKBP1A | |
| SCHEMBL17884595 | 0.85 | SIGMAR1 (0.52) | SIGMAR1KMT2AMEN1POLBFKBP1A | |
| SCHEMBL7395808 | 0.83 | FKBP1A (0.52) | SIGMAR1KMT2AMEN1POLBFKBP1A | |
| SCHEMBL17884409 | 0.83 | FKBP1A (0.52) | SIGMAR1KMT2AMEN1POLBFKBP1A | |
| SCHEMBL21593860 | 0.82 | SIGMAR1 (0.51) | SIGMAR1KMT2AMEN1POLBFKBP1A | |
| SCHEMBL21471518 | 0.81 | FKBP1A (0.67) | KMT2AMEN1FKBP1ASMN1; SMN2ALDH1A1 | |
| SCHEMBL21540292 | 0.79 | FKBP1A (0.54) | SIGMAR1KMT2AMEN1POLBFKBP1A | |
| SCHEMBL5741062 | 0.79 | POLB (0.51) | SIGMAR1KMT2AMEN1POLBFKBP1A | |
| SCHEMBL5741069 | 0.79 | POLB (0.51) | SIGMAR1KMT2AMEN1POLBFKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3030556-B1 | SELECTIVE FKBP51 LIGANDS FOR TREATMENT OF PSYCHIATRIC DISORDERS | UNIV DARMSTADT TECH (DE) | 2019-10-30 | — | — | EP | disclosed |