Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | ANPEP | P15144 | 1/20 | 0.31 |
| ▸ | FNTA | P49354 | 2/20 | 0.30 |
| ▸ | FNTB | P49356 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3390185 | 0.83 | ACE (0.33) | ATMACE | |
| SCHEMBL17336127 | 0.83 | ACE (0.33) | ATMACE | |
| SCHEMBL16824591 | 0.75 | HSD17B10 (0.42) | ATMPOLBCYP3A4KMT2A | |
| SCHEMBL27390283 | 0.75 | TSHR (0.34) | ATMPOLBACE | |
| SCHEMBL247111 | 0.71 | ACE (0.58) | ATMPOLBACECYP3A4KMT2A | |
| SCHEMBL28727117 | 0.71 | ACE (0.58) | ATMPOLBACECYP3A4KMT2A | |
| SCHEMBL11890821 | 0.71 | CHRNB2 (0.32) | — | |
| SCHEMBL992740 | 0.69 | — | — | |
| SCHEMBL17541277 | 0.69 | — | — | |
| SCHEMBL29183121 | 0.67 | TSHR (0.34) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3030556-B1 | SELECTIVE FKBP51 LIGANDS FOR TREATMENT OF PSYCHIATRIC DISORDERS | UNIV DARMSTADT TECH (DE) | 2019-10-30 | — | — | EP | disclosed |