Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 17/20 | 0.62 |
| ▸ | FKBP5 | Q13451 | 13/20 | 0.62 |
| ▸ | FKBP1B | P68106 | 2/20 | 0.62 |
| ▸ | FKBP4 | Q02790 | 3/20 | 0.61 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.60 |
| ▸ | HRH2 | P25021 | 1/20 | 0.60 |
| ▸ | HTR1D | P28221 | 1/20 | 0.60 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.60 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.60 |
| ▸ | FKBP2 | P26885 | 1/20 | 0.60 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19719614 | 1.00 | FKBP1A (0.62) | FKBP1AFKBP5FKBP1BFKBP4TMEM97 | |
| SCHEMBL16595016 | 1.00 | FKBP1A (0.62) | FKBP1AFKBP5FKBP1BFKBP4TMEM97 | |
| SCHEMBL18120738 | 0.89 | FKBP5 (0.55) | FKBP1AFKBP5FKBP1BFKBP4TMEM97 | |
| SCHEMBL21518714 | 0.89 | FKBP1A (0.57) | FKBP1AFKBP5FKBP1BFKBP4TMEM97 | |
| SCHEMBL21518711 | 0.89 | FKBP1A (0.57) | FKBP1AFKBP5FKBP1BFKBP4TMEM97 | |
| SCHEMBL19719552 | 0.88 | FKBP5 (0.68) | FKBP1AFKBP5FKBP1BFKBP4TMEM97 | |
| SCHEMBL16586103 | 0.88 | FKBP5 (0.68) | FKBP1AFKBP5FKBP1BFKBP4TMEM97 | |
| SCHEMBL16586108 | 0.88 | FKBP5 (0.68) | FKBP1AFKBP5FKBP1BFKBP4TMEM97 | |
| SCHEMBL21518662 | 0.87 | FKBP1A (0.56) | FKBP1AFKBP5FKBP1BFKBP4TMEM97 | |
| SCHEMBL21518689 | 0.87 | FKBP1A (0.56) | FKBP1AFKBP5FKBP1BFKBP4TMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3030556-B1 | SELECTIVE FKBP51 LIGANDS FOR TREATMENT OF PSYCHIATRIC DISORDERS | UNIV DARMSTADT TECH (DE) | 2019-10-30 | — | — | EP | disclosed |