Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 17/20 | 0.62 |
| ▸ | FKBP5 | Q13451 | 13/20 | 0.62 |
| ▸ | FKBP1B | P68106 | 2/20 | 0.62 |
| ▸ | FKBP4 | Q02790 | 3/20 | 0.61 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.60 |
| ▸ | HRH2 | P25021 | 1/20 | 0.60 |
| ▸ | HTR1D | P28221 | 1/20 | 0.60 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.60 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.60 |
| ▸ | FKBP2 | P26885 | 1/20 | 0.60 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21540169 | 1.00 | FKBP1A (0.62) | FKBP1AFKBP5FKBP1BFKBP4TMEM97 | |
| SCHEMBL19719614 | 1.00 | FKBP1A (0.62) | FKBP1AFKBP5FKBP1BFKBP4TMEM97 | |
| SCHEMBL18120738 | 0.89 | FKBP5 (0.55) | FKBP1AFKBP5FKBP1BFKBP4TMEM97 | |
| SCHEMBL21518714 | 0.89 | FKBP1A (0.57) | FKBP1AFKBP5FKBP1BFKBP4TMEM97 | |
| SCHEMBL21518711 | 0.89 | FKBP1A (0.57) | FKBP1AFKBP5FKBP1BFKBP4TMEM97 | |
| SCHEMBL19719552 | 0.88 | FKBP5 (0.68) | FKBP1AFKBP5FKBP1BFKBP4TMEM97 | |
| SCHEMBL16586103 | 0.88 | FKBP5 (0.68) | FKBP1AFKBP5FKBP1BFKBP4TMEM97 | |
| SCHEMBL16586108 | 0.88 | FKBP5 (0.68) | FKBP1AFKBP5FKBP1BFKBP4TMEM97 | |
| SCHEMBL21518662 | 0.87 | FKBP1A (0.56) | FKBP1AFKBP5FKBP1BFKBP4TMEM97 | |
| SCHEMBL21518689 | 0.87 | FKBP1A (0.56) | FKBP1AFKBP5FKBP1BFKBP4TMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3030556-B1 | SELECTIVE FKBP51 LIGANDS FOR TREATMENT OF PSYCHIATRIC DISORDERS | UNIV DARMSTADT TECH (DE) | 2019-10-30 | — | — | EP | claimed |
| US-10246413-B2 | Selective FKBP51 ligands for treatment of psychiatric disorders | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2019-04-02 | — | — | US | disclosed |
| US-20180072667-A1 | SELECTIVE FKBP51 LIGANDS FOR TREATMENT OF PSYCHIATRIC DISORDERS | HAUSCH, FELIX (DE) | 2018-03-15 | — | — | US | disclosed |
| US-9845292-B2 | Selective FKBP51 ligands for treatment of psychiatric disorders | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2017-12-19 | — | — | US | disclosed |
| US-20160289184-A1 | SELECTIVE FKBP51 LIGANDS FOR TREATMENT OF PSYCHIATRIC DISORDERS | HAUSCH, FELIX (DE) | 2016-10-06 | — | — | US | disclosed |
| WO-2015039758-A1 | SELECTIVE FKBP51 LIGANDS FOR TREATMENT OF PSYCHIATRIC DISORDERS | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2015-03-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180072667-A1 | SELECTIVE FKBP51 LIGANDS FOR TREATMENT OF PSYCHIATRIC DISORDERS | FKBP5, FKBP1A, FKBP3 | FKBP1A 2/4885FKBP5 1/4885FKBP1B 4/4885 |
| US-10246413-B2 | Selective FKBP51 ligands for treatment of psychiatric disorders | FKBP5, FKBP1A, FKBP3 | FKBP1A 2/4885FKBP5 1/4885FKBP1B 4/4885 |
| US-20160289184-A1 | SELECTIVE FKBP51 LIGANDS FOR TREATMENT OF PSYCHIATRIC DISORDERS | FKBP5, FKBP1A, FKBP1B | FKBP1A 2/4885FKBP5 1/4885FKBP1B 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.