Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2154012 | 1.00 | HPGD (0.43) | HPGDERCC5FEN1NPC1RAB9A | |
| SCHEMBL8846182 | 1.00 | HPGD (0.43) | HPGDERCC5FEN1NPC1RAB9A | |
| SCHEMBL6626532 | 0.82 | LMNA (0.47) | HPGDNPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL2154230 | 0.82 | LMNA (0.47) | HPGDNPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL2154229 | 0.82 | LMNA (0.47) | HPGDNPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL8846269 | 0.81 | NPC1 (0.41) | HPGDERCC5FEN1NPC1RAB9A | |
| SCHEMBL8846279 | 0.81 | NPC1 (0.41) | HPGDERCC5FEN1NPC1RAB9A | |
| SCHEMBL2154243 | 0.81 | ALDH1A1 (0.47) | HPGDERCC5FEN1RAB9APOLB | |
| SCHEMBL2154238 | 0.81 | ALDH1A1 (0.47) | HPGDERCC5FEN1RAB9APOLB | |
| SCHEMBL19999190 | 0.79 | SMN1; SMN2 (0.43) | HPGDERCC5FEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130040993-A1 | FUNGICIDE HYDROXIMOYL-HETEROCYCLES DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2013-02-14 | — | — | US | claimed |
| EP-2519502-A2 | FUNGICIDAL HYDROXIMOYL-HETEROCYCLES DERIVATIVES | Bayer CropScience AG (DE) | 2012-11-07 | — | — | EP | claimed |
| WO-2011080254-A2 | FUNGICIDE HYDROXIMOYL-HETEROCYCLES DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2011-07-07 | — | — | WO | claimed |
| US-9000012-B2 | Fungicide hydroximoyl-heterocycles derivatives | BAYER CROPSCIENCE AG (DE) | 2015-04-07 | — | — | US | disclosed |
| US-20130040993-A1 | FUNGICIDE HYDROXIMOYL-HETEROCYCLES DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2013-02-14 | — | — | US | disclosed |
| EP-2519502-A2 | FUNGICIDAL HYDROXIMOYL-HETEROCYCLES DERIVATIVES | Bayer CropScience AG (DE) | 2012-11-07 | — | — | EP | disclosed |
| WO-2011080254-A2 | FUNGICIDE HYDROXIMOYL-HETEROCYCLES DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2011-07-07 | — | — | WO | disclosed |
| US-5693859-A | REACTING ORTHO-SUBSTITUTED PHENYL ALPHA-KETO ACID HALIDE WITH AN AMINE YIELDS SUBSTITUTED PHENYL ALPHA-KETAMIDE | SHIONOGI & CO., LTD. (JP) | 1997-12-02 | — | — | US | disclosed |
| EP-0535928-B1 | Process for producing intermediates for use in production of alkoxyiminoacetamides | SHIONOGI & CO (JP) | 1996-05-01 | — | — | EP | disclosed |
| US-5502252-A | FUNGICIDES FOR RICE AND CUCUMBERS | SHIONOGI & CO., LTD. (JP) | 1996-03-26 | — | — | US | disclosed |
| US-5387714-A | Alpha-keto acid halide intermediate | SHIONOGI & CO., LTD. (JP) | 1995-02-07 | — | — | US | disclosed |
| EP-0535928-A2 | Process for producing intermediates for use in production of alkoxyiminoacetamides | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1993-04-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130040993-A1 | FUNGICIDE HYDROXIMOYL-HETEROCYCLES DERIVATIVES | HAAO, HPD, CYP51A1 | HPGD 531/4885ERCC5 2816/4885FEN1 1926/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.