Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27365590 | 0.88 | PRMT3 (0.36) | EPHX1 | |
| SCHEMBL3314760 | 0.86 | EPHX1 (0.33) | EPHX1KDM4EALDH1A1GAAHPGD | |
| SCHEMBL10811942 | 0.85 | EPHX1 (0.48) | EPHX1KDM4EHSD17B10DRD2DRD4 | |
| SCHEMBL21501557 | 0.85 | EPHX1 (0.48) | EPHX1KDM4EHSD17B10DRD2DRD4 | |
| SCHEMBL25792518 | 0.85 | PRMT3 (0.33) | EPHX1MAOAMAOBDRD2DRD4 | |
| SCHEMBL14996455 | 0.85 | — | — | |
| SCHEMBL22224039 | 0.83 | MAOA (0.35) | EPHX1MAOAMAOBDRD2DRD4 | |
| SCHEMBL12305100 | 0.81 | HTR1B (0.39) | GAAMAOAMAOBDRD3CYP1A2 | |
| SCHEMBL9024746 | 0.81 | PIK3CD (0.37) | MAOAMAOBDRD2DRD3 | |
| SCHEMBL12354538 | 0.81 | PIK3CD (0.37) | MAOAMAOBDRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3030556-B1 | SELECTIVE FKBP51 LIGANDS FOR TREATMENT OF PSYCHIATRIC DISORDERS | UNIV DARMSTADT TECH (DE) | 2019-10-30 | — | — | EP | disclosed |