SCHEMBL9024746

SCHEMBL9024746

CCCN(CCOC)CCOC

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PIK3CD O00329 1/20 0.37
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33
HRH3 Q9Y5N1 1/20 0.31
HTR1A P08908 1/20 0.30
DRD2 P14416 1/20 0.30
DRD3 P35462 1/20 0.30
EBP Q15125 1/20 0.30
TMEM97 Q5BJF2 1/20 0.30
SIGMAR1 Q99720 1/20 0.30
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12354538 1.00 PIK3CD (0.37) PIK3CDMEN1KMT2AMAOAMAOB
Hydrochloric Acid SCHEMBL14801600 0.97 PIK3CD (0.36) PIK3CDMEN1KMT2AMAOAMAOB
Bromide SCHEMBL14801362 0.97 PIK3CD (0.36) PIK3CDMEN1KMT2AMAOAMAOB
SCHEMBL12305100 0.90 HTR1B (0.39) MAOAMAOBHTR1ADRD3
SCHEMBL12663243 0.89 MEN1 (0.37) PIK3CDMEN1KMT2APOLB
SCHEMBL12131662 0.88 LCK (0.34) PIK3CDMEN1KMT2A
SCHEMBL15800488 0.88 LMNA (0.43) PIK3CDMEN1KMT2AHRH3POLB
SCHEMBL16592400 0.88 MEN1 (0.33) PIK3CDMEN1KMT2APOLB
SCHEMBL16838261 0.88 HSD17B10 (0.35) PIK3CDMEN1KMT2A
SCHEMBL1292539 0.87 PIK3CD (0.43) PIK3CDMEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3915987-B1 ALKYL-AMINE HARMINE DERIVATIVES FOR PROMOTING BONE GROWTH OSTEOQC INC (CA) 2023-12-13 EP disclosed
US-11309106-B2 Device protected by PTC element Liffelfuse Japan G. K. (JP) 2022-04-19 US disclosed
EP-3915987-A1 ALKYL-AMINE HARMINE DERIVATIVES FOR PROMOTING BONE GROWTH Osteoqc Inc. (CA) 2021-12-01 EP disclosed
EP-2968284-B1 ALKYL-AMINE HARMINE DERIVATIVES FOR PROMOTING BONE GROWTH OSTEOQC INC (CA) 2021-04-21 EP disclosed
EP-3570300-A1 DEVICE PROTECTED BY PTC ELEMENT Littelfuse Japan G.K. (JP) 2019-11-20 EP disclosed
US-20170298059-A1 COMPOUNDS FOR BONE GROWTH OSSIFI THERAPEUTICS LLC 2017-10-19 US disclosed
EP-2725075-B1 Radiation curable inkjet inks AGFA-GEVAERT (BE) 2017-07-26 EP disclosed
US-9540365-B2 Compounds for bone growth OSTEOQC INC. (CA) 2017-01-10 US disclosed
US-20150218398-A1 RADIATION CURABLE INKJET INKS AGFA-GEVAERT (BE) 2015-08-06 US disclosed
US-20140288068-A1 ALKYL-AMINE HARMINE DERIVATIVES FOR PROMOTING BONE GROWTH OSSIFI INC. (US) 2014-09-25 US disclosed
US-8455497-B2 Inhibitors of aspartyl protease VERTEX PHARMACEUTICALS INCORPORATED (US) 2013-06-04 US disclosed
EP-1485377-B9 PYRANONES USEFUL AS ATM INHIBITORS KUDOS PHARM LTD (GB) 2010-10-06 EP disclosed
US-7642245-B2 Antibacterial compounds having a (pyrrole carboxamide)-(benzamide)-(imidazole carboxamide) motif OSCIENT PHARMACEUTICALS CORPORATION (US) 2010-01-05 US disclosed
EP-1485377-B1 PYRANONES USEFUL AS ATM INHIBITORS KUDOS PHARM LTD (GB) 2009-12-09 EP disclosed
WO-2007038669-A9 DIARYLAMINE-CONTAINING COMPOUNDS AND COMPOSITIONS, AND THEIR USE AS MODULATORS OF C-KIT RECEPTORS IRM LLC 2008-05-29 WO disclosed
US-20070142268-A1 Antibacterial compounds having a (pyrrole carboxamide)-(benzamide)-(imidazole carboxamide) motif OSCIENT PHARMACEUTICALS CORPORATION (US) 2007-06-21 US disclosed
WO-2007038669-A2 DIARYLAMINE-CONTAINING COMPOUNDS AND COMPOSITIONS, AND THEIR USE AS MODULATORS OF C-KIT RECEPTORS IRM LLC (BM) 2007-04-05 WO disclosed
EP-0501693-B1 Isoquinoline derivatives BANYU PHARMA CO LTD (JP) 1996-08-28 EP disclosed
US-5362736-A Alkoxy derivatives for cardiovascular disorders BANYU PHARMACEUTICAL CO., LTD. (JP) 1994-11-08 US disclosed
EP-0501693-A1 Isoquinoline derivatives BANYU PHARMACEUTICAL CO., LTD. (JP) 1992-09-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070142268-A1 Antibacterial compounds having a (pyrrole carboxamide)-(benzamide)-(imidazole carboxamide) motif AADAC, MRPL21, HDAC6 PIK3CD 4277/4885MEN1 3199/4885KMT2A 1789/4885
US-20170298059-A1 COMPOUNDS FOR BONE GROWTH FGF1, FGF2, BMP2 PIK3CD 3765/4885MEN1 451/4885KMT2A 3833/4885
US-20140288068-A1 ALKYL-AMINE HARMINE DERIVATIVES FOR PROMOTING BONE GROWTH TPH1, TPH2, HTR5A PIK3CD 4448/4885MEN1 864/4885KMT2A 661/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.