Sugi Predict

Sugi Predict / Compounds / SCHEMBL2154374

SCHEMBL2154374

SCHEMBL2154374

CNC(=O)/C(=N/O)c1ccccc1Oc1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CTNNB1 P35222 2/20 0.51
▸ RAB9A P51151 1/20 0.48
▸ L3MBTL1 Q9Y468 4/20 0.47
▸ MEN1 O00255 3/20 0.47
▸ KMT2A Q03164 3/20 0.47
▸ NPSR1 Q6W5P4 1/20 0.47
▸ SMN1; SMN2 Q16637 1/20 0.43
▸ GAA P10253 3/20 0.43
▸ TSHR P16473 2/20 0.43
▸ LMNA P02545 1/20 0.43
▸ MAPT P10636 1/20 0.43
▸ TCF4 P15884 1/20 0.43
▸ TCF7L2 Q9NQB0 1/20 0.43
▸ ALDH1A1 P00352 4/20 0.42
▸ KDM4E B2RXH2 1/20 0.42
▸ MAPK1 P28482 2/20 0.42
▸ TDP1 Q9NUW8 2/20 0.42
▸ MAPK8 P45983 1/20 0.42
▸ HSD17B10 Q99714 1/20 0.42
▸ HPGD P15428 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2154375 1.00 CTNNB1 (0.51) CTNNB1RAB9AL3MBTL1MEN1KMT2A
SCHEMBL2154270 0.90 LMNA (0.46) CTNNB1RAB9AL3MBTL1MEN1KMT2A
SCHEMBL2154272 0.90 LMNA (0.46) CTNNB1RAB9AL3MBTL1MEN1KMT2A
Metominostrobin SCHEMBL29736874 0.86 RAB9A (0.49) CTNNB1RAB9AL3MBTL1MEN1KMT2A
Metominostrobin SCHEMBL29376726 0.86 RAB9A (0.49) CTNNB1RAB9AL3MBTL1MEN1KMT2A
Metominostrobin SCHEMBL18652 0.86 RAB9A (0.49) CTNNB1RAB9AL3MBTL1MEN1KMT2A
Metominostrobin SCHEMBL54680 0.86 RAB9A (0.49) CTNNB1RAB9AL3MBTL1MEN1KMT2A
Metominostrobin SCHEMBL912965 0.86 RAB9A (0.49) CTNNB1RAB9AL3MBTL1MEN1KMT2A
SCHEMBL25923669 0.85 CTNNB1 (0.48) CTNNB1RAB9AL3MBTL1MEN1KMT2A
Metominostrobin SCHEMBL28036690 0.85 RAB9A (0.48) CTNNB1RAB9AL3MBTL1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130040993-A1 FUNGICIDE HYDROXIMOYL-HETEROCYCLES DERIVATIVES BAYER CROPSCIENCE AG (DE) 2013-02-14 — — US claimed
EP-2519502-A2 FUNGICIDAL HYDROXIMOYL-HETEROCYCLES DERIVATIVES Bayer CropScience AG (DE) 2012-11-07 — — EP claimed
WO-2011080254-A2 FUNGICIDE HYDROXIMOYL-HETEROCYCLES DERIVATIVES BAYER CROPSCIENCE AG (DE) 2011-07-07 — — WO claimed
US-9000012-B2 Fungicide hydroximoyl-heterocycles derivatives BAYER CROPSCIENCE AG (DE) 2015-04-07 — — US disclosed
US-20130040993-A1 FUNGICIDE HYDROXIMOYL-HETEROCYCLES DERIVATIVES BAYER CROPSCIENCE AG (DE) 2013-02-14 — — US disclosed
EP-2519502-A2 FUNGICIDAL HYDROXIMOYL-HETEROCYCLES DERIVATIVES Bayer CropScience AG (DE) 2012-11-07 — — EP disclosed
WO-2011080254-A2 FUNGICIDE HYDROXIMOYL-HETEROCYCLES DERIVATIVES BAYER CROPSCIENCE AG (DE) 2011-07-07 — — WO disclosed
CN-1051760-C (E) Process for producing (E) -alkoxyimino or hydroxyimino-acetamide compound SHIONOGI PHARMACEUTICAL K K (JP) 2000-04-26 — — CN disclosed
CN-1223248-A Process for producing (E)-alkoxyimino or hydroxyimino-acetamide compounds and intermediates therefor SHIONOGI & CO (JP) 1999-07-21 — — CN disclosed
US-5650539-A ALKYLATION, ESTERIFICATION, DEESTERIFICATION, AMIDATION, FUNGICIDES SHIONOGI & CO., LTD. (JP) 1997-07-22 — — US disclosed
EP-0596692-B1 A process for producing (E)-alkoxyimino or hydroxyiminoacetamide compounds and intermediates therefor SHIONOGI & CO (JP) 1997-06-04 — — EP disclosed
US-5488159-A AMIDATION, METHYLATION, FUNGICIDE SHIONOGI & CO., LTD. (JP) 1996-01-30 — — US disclosed
US-5442063-A Agricultural fungicides SHIONOGI & CO., LTD. (JP) 1995-08-15 — — US disclosed
CN-1103064-A (E) Process for producing (E) -alkoxyimino or hydroxyimino-acetamide compound and intermediate thereof SHIONOGI & CO (JP) 1995-05-31 — — CN disclosed
US-5380913-A E-Isomers of 2-methoxyimino-N-methyl-2-phenoxyphenylacetamides and alkyl 2-methoxyimino-2-phenoxyphenylacetates produced by reacting Z-isomers with hydrogen chloride or hydrochloric, sulfuric or toluenesulfonic acid in methyl, ethyl or butyl alc SHIONOGI & CO., LTD. (JP) 1995-01-10 — — US disclosed
EP-0606924-A1 Process for producing E-isomers of methoxyminoacetamide compounds SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) 1994-07-20 — — EP disclosed
EP-0605392-A1 Process for producing methoxyminoacetamide compounds SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) 1994-07-06 — — EP disclosed
EP-0596692-A2 A process for producing (E)-alkoxyimino or hydroxyiminoacetamide compounds and intermediates therefor SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) 1994-05-11 — — EP disclosed
US-5183921-A Agricultural fungicides SHIONOGI & CO., LTD. (JP) 1993-02-02 — — US disclosed
EP-0468775-A1 Process for producing methoxyiminoacetamide compounds and intermediates SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) 1992-01-29 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130040993-A1 FUNGICIDE HYDROXIMOYL-HETEROCYCLES DERIVATIVES HAAO, HPD, CYP51A1 CTNNB1 4540/4885RAB9A 3787/4885L3MBTL1 3027/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.