Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2154883 | 1.00 | ALDH1A1 (0.40) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL16958104 | 0.92 | TDP1 (0.39) | ALDH1A1KMT2AMEN1SMN1; SMN2TDP1 | |
| SCHEMBL6190625 | 0.74 | HSP90AA1 (0.44) | ALDH1A1MAPTKMT2ALMNAPOLB | |
| SCHEMBL11520409 | 0.74 | TDP1 (0.47) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL6377367 | 0.74 | ALDH1A1 (0.39) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL7335158 | 0.73 | HSP90AA1 (0.49) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL529103 | 0.72 | PTGDR2 (0.36) | HSP90AA1 | |
| SCHEMBL9644212 | 0.72 | PTGDR2 (0.36) | HSP90AA1 | |
| SCHEMBL14655347 | 0.71 | POLB (0.41) | ALDH1A1MAPTKMT2AMEN1POLB | |
| SCHEMBL436786 | 0.70 | NPSR1 (0.33) | ALDH1A1KMT2AMEN1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2513064-A2 | COMPOUNDS, COMPOSITIONS AND METHODS FOR CONTROLLING BIOFILMS | Katholieke Universiteit Leuven, K.U. Leuven R&D (BE) | 2012-10-24 | — | — | EP | claimed |
| WO-2011080132-A2 | COMPOUNDS, COMPOSITIONS AND METHODS FOR CONTROLLING BIOFILMS | KATHOLIEKE UNIVERSITEIT LEUVEN, K.U. LEUVEN R&D (BE) | 2011-07-07 | — | — | WO | claimed |