SCHEMBL2154571

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14474905	0.91	L3MBTL1 (0.51)	MAPTKDM4EKMT2AL3MBTL1CYP1A2
	SCHEMBL14475528	0.91	L3MBTL1 (0.51)	MAPTKDM4EKMT2AL3MBTL1CYP1A2
	SCHEMBL16183257	0.90	PDE5A (0.59)	MAPTKDM4EKMT2AMEN1POLB
	SCHEMBL14475416	0.90	RXFP1 (0.61)	MAPTKDM4EKMT2AMEN1POLB
	SCHEMBL14359165	0.89	L3MBTL1 (0.49)	MAPTKDM4EKMT2AL3MBTL1CYP1A2
	SCHEMBL14474008	0.89	PDE5A (0.58)	MAPTKDM4EKMT2AL3MBTL1CYP1A2
	SCHEMBL14727142	0.89	PDE5A (0.58)	MAPTKDM4EKMT2AMEN1L3MBTL1
	SCHEMBL14726035	0.89	CYP1A2 (0.63)	MAPTKDM4EL3MBTL1CYP1A2CYP3A4
	SCHEMBL14474895	0.89	BRAF (0.50)	MAPTKDM4EKMT2AMEN1POLB
	SCHEMBL14474918	0.88	L3MBTL1 (0.48)	MAPTKDM4EKMT2AL3MBTL1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.