SCHEMBL2154688

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL27953880	0.83	PDE5A (0.60)	GBA1CYP1A2CYP3A4ALDH1A1CLK4
	SCHEMBL16183305	0.83	GBA1 (0.49)	GBA1CYP1A2CYP3A4ALDH1A1CLK4
	SCHEMBL2155318	0.83	KMT2A (0.55)	GBA1CYP1A2CYP3A4ALDH1A1CLK4
	SCHEMBL2154644	0.80	ABCG2 (0.56)	CYP1A2CYP3A4ALDH1A1CLK4TSHR
	SCHEMBL14359013	0.80	CYP1A2 (0.70)	GBA1CYP1A2CYP3A4ALDH1A1CLK4
	SCHEMBL14727925	0.79	KMT2A (0.51)	CYP1A2CYP3A4ALDH1A1CLK4TSHR
	SCHEMBL16183771	0.79	ABCG2 (0.55)	GBA1CYP1A2CYP3A4ALDH1A1CLK4
	SCHEMBL14727483	0.78	ADORA2A (0.36)	CYP3A4
	SCHEMBL14727715	0.77	CCNE2 (0.57)	GBA1CYP1A2CYP3A4ALDH1A1CLK4
	SCHEMBL14358664	0.77	CYP19A1 (0.56)	GBA1CYP1A2CYP3A4CYP2D6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.