SCHEMBL2154644

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2154752	0.90	ABCG2 (0.56)	ABCG2CYP11B2CYP17A1CYP11B1CYP3A4
	SCHEMBL14358664	0.86	CYP19A1 (0.56)	ABCG2CYP11B2CYP11B1CYP3A4MAPT
	SCHEMBL7813723	0.86	MTNR1A (0.56)	ABCG2CYP3A4MAPTMEN1KMT2A
	SCHEMBL20273439	0.86	ABCG2 (0.57)	ABCG2CYP11B2CYP17A1CYP11B1CYP3A4
	SCHEMBL2154551	0.85	ABCG2 (0.56)	ABCG2CYP11B2CYP17A1CYP11B1CYP3A4
	SCHEMBL2154805	0.85	CYP17A1 (0.58)	ABCG2CYP11B2CYP17A1CYP11B1CYP3A4
	SCHEMBL14474404	0.85	ABCG2 (0.62)	ABCG2CYP11B2CYP17A1CYP11B1CYP3A4
	SCHEMBL14359734	0.82	CYP1A2 (0.67)	ABCG2CYP11B2CYP17A1CYP11B1CYP3A4
	SCHEMBL14474398	0.81	MAPT (0.71)	ABCG2CYP11B2CYP17A1CYP11B1CYP3A4
	SCHEMBL14475231	0.81	MEN1 (0.54)	ABCG2CYP11B2CYP17A1CYP11B1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.