Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | KDM6B | O15054 | 1/20 | 0.33 |
| ▸ | KDM5C | P41229 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.33 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11529618 | 0.83 | ALDH1A1 (0.56) | LMNASLC15A2TDP1TSHRALDH1A1 | |
| SCHEMBL18083835 | 0.81 | TSHR (0.65) | LMNASLC15A2TDP1TSHRHDAC2 | |
| SCHEMBL21553552 | 0.78 | TDP1 (0.44) | LMNATDP1TSHRHDAC2HDAC3 | |
| SCHEMBL18937913 | 0.77 | TSHR (0.40) | LMNATDP1TSHRHDAC2 | |
| SCHEMBL6536912 | 0.77 | TDP1 (0.56) | TDP1TSHRALDH1A1HDAC2 | |
| SCHEMBL16303292 | 0.75 | TSHR (0.72) | LMNASLC15A2TDP1TSHRALDH1A1 | |
| SCHEMBL301539 | 0.75 | — | — | |
| SCHEMBL13385714 | 0.73 | — | — | |
| SCHEMBL26737546 | 0.72 | HDAC2 (0.54) | LMNATDP1TSHRHDAC2HDAC3 | |
| SCHEMBL9858502 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3494157-B1 | STABILIZERS FOR BROMINATED POLYMERIC FLAME RETARDANTS | BROMINE COMPOUNDS LTD (IL) | 2021-03-03 | — | — | EP | disclosed |
| WO-2020065408-A1 | SULFOMALEIMIDE-BASED LINKERS AND CORRESPONDING CONJUGATES | PIERRE FABRE MEDICAMENT (FR) | 2020-04-02 | — | — | WO | disclosed |
| EP-3395358-B1 | INSULIN ANALOG DIMERS | UNIV INDIANA RES & TECH CORP (US) | 2019-11-06 | — | — | EP | disclosed |