Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21548083 | 0.78 | LMNA (0.44) | TDP1TSHRLMNAHDAC2HDAC3 | |
| SCHEMBL18083835 | 0.78 | TSHR (0.65) | TDP1TSHRLMNAHDAC2 | |
| SCHEMBL18937913 | 0.74 | TSHR (0.40) | TDP1TSHRLMNAHDAC2 | |
| SCHEMBL6536912 | 0.74 | TDP1 (0.56) | TDP1TSHRHDAC2HIF1A | |
| Glutaral SCHEMBL2258172 | 0.71 | TSHR (0.62) | TDP1TSHRLMNAHDAC2HIF1A | |
| SCHEMBL26737546 | 0.69 | HDAC2 (0.54) | TDP1TSHRLMNAHDAC2HDAC3 | |
| SCHEMBL28409672 | 0.69 | — | — | |
| SCHEMBL11427476 | 0.69 | — | — | |
| SCHEMBL12126147 | 0.69 | — | — | |
| SCHEMBL9143482 | 0.68 | ALDH1A1 (0.35) | TDP1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2895200-B1 | MULTIMERIC OLIGONUCLEOTIDE COMPOUNDS | TRANSLATE BIO MA INC (US) | 2019-11-06 | — | — | EP | disclosed |