SCHEMBL11529618

SCHEMBL11529618

CC(=O)CCSSCCC(C)=O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.56
TSHR P16473 3/20 0.56
LMNA P02545 4/20 0.53
SLC15A2 Q16348 1/20 0.53
TDP1 Q9NUW8 2/20 0.39
KMT2A Q03164 1/20 0.38
HSD17B10 Q99714 1/20 0.38
EGLN1 Q9GZT9 2/20 0.38
ACHE P22303 1/20 0.38
PAOX Q6QHF9 1/20 0.38
KDM4E B2RXH2 1/20 0.38
KDM6B O15054 1/20 0.38
KDM5C P41229 1/20 0.38
PHF8 Q9UPP1 1/20 0.38
KDM2A Q9Y2K7 1/20 0.38
TRPA1 O75762 1/20 0.37
FOLH1 Q04609 1/20 0.34
FFAR3 O14843 1/20 0.33
HDAC3 O15379 1/20 0.33
HDAC1 Q13547 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16303292 0.91 TSHR (0.72) ALDH1A1TSHRLMNASLC15A2TDP1
SCHEMBL13385714 0.89
SCHEMBL17520224 0.87 TSHR (0.50) ALDH1A1TSHRLMNASLC15A2TDP1
SCHEMBL10064430 0.85
SCHEMBL17124818 0.84 TSHR (0.42) ALDH1A1TSHRLMNASLC15A2TDP1
SCHEMBL15031801 0.83 TSHR (0.40) ALDH1A1TSHRLMNASLC15A2
SCHEMBL9889751 0.83 LMNA (0.48) ALDH1A1TSHRLMNASLC15A2EGLN1
SCHEMBL21548083 0.83 LMNA (0.44) ALDH1A1TSHRLMNASLC15A2TDP1
SCHEMBL12192206 0.81 CES2 (0.55) ALDH1A1TSHRTDP1KMT2AHSD17B10
SCHEMBL15604713 0.81 ALDH1A1 (0.48) ALDH1A1TSHRLMNASLC15A2TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112014503-A Method for detecting acetonitrile in organized waste gas 浙江鑫泰检测技术有限公司 2020-12-01 CN claimed
US-10793779-B2 Method for separating soluble organic matter in petroleum coke SHANDONG CHAMBROAD PETROCHEMICALS CO., LTD. (CN) 2020-10-06 US claimed
US-20190078025-A1 METHOD FOR SEPARATING SOLUBLE ORGANIC MATTER IN PETROLEUM COKE SHANDONG CHAMBROAD PETROCHEMICALS CO., LTD. (CN) 2019-03-14 US claimed
CN-106582058-B A method of separation petroleum coke Soluble Organic Matter 山东京博石油化工有限公司 2018-10-30 CN claimed
CN-106582058-A Method for separating soluble organic matters from petroleum coke 山东京博石油化工有限公司 2017-04-26 CN claimed
US-11384103-B2 Silane, rubber mixture containing the silane, and vehicle tire having the rubber mixture in at least one component CONTINENTAL REIFEN DEUTSCHLAND GMBH (DE) 2022-07-12 US disclosed
CN-216143388-U Cold-resistant heat-resistant natural gas pipeline with good ageing resistance effect 沧州中铁装备制造材料有限公司 2022-03-29 CN disclosed
CN-215370483-U Prevent PVC strake that ftractures convenient to installation 青岛君联汽车部件有限公司 2021-12-31 CN disclosed
CN-214127169-U Household PVC (polyvinyl chloride) gloves 江苏尤佳手套有限公司 2021-09-07 CN disclosed
CN-213895696-U High-temperature-resistant adhesive tape with flame-retardant function 深圳市创丰环保包装材料有限公司 2021-08-06 CN disclosed
CN-212936173-U Antiskid sound picking pad for ancient lyre 陈乃峰 2021-04-09 CN disclosed
CN-112175327-A Preparation method of PVC (polyvinyl chloride) plastic for wear-resistant and antibacterial rubber shoes 界首市旭升塑胶制品有限公司 2021-01-05 CN disclosed
CN-103263123-A High-temperature-resistance zipper JIANGSU HONGDA ZIPPER MANUFACTURE CO LTD 2013-08-28 CN disclosed
EP-2508590-A1 LUBRICATING OIL COMPOSITION Idemitsu Kosan Co., Ltd. (JP) 2012-10-10 EP disclosed
US-20120238481-A1 LUBRICATING OIL COMPOSITION IDEMITSU KOSAN CO., LTD. (JP) 2012-09-20 US disclosed
US-20120238481-A1 LUBRICATING OIL COMPOSITION IDEMITSU KOSAN CO., LTD. (JP) 2012-09-20 US disclosed
US-4141942-A WET SPINNING AT INTERFACE OF TWO-PHASE COAGULATION BATH IDEMITSU KOSAN CO., LTD. (JP) 1979-02-27 US disclosed
US-4115482-A PESTICIDES EXXON RESEARCH AND ENGINEERING COMPANY (US) 1978-09-19 US disclosed
US-4102959-A Process for preparing film by wet method IDEMITSU KOSAN COMPANY, LTD. (JP) 1978-07-25 US disclosed
US-4004405-A FABRIC, POLYETHYLENE TEREPHTHALATE DAN RIVER, INCORPORATED (US) 1977-01-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11384103-B2 Silane, rubber mixture containing the silane, and vehicle tire having the rubber mixture in at least one component NR4A1, NR0B1, NR2E1 ALDH1A1 3319/4885TSHR 640/4885LMNA 811/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.