Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SYK | P43405 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CTSL | P07711 | 2/20 | 0.42 |
| ▸ | CTSS | P25774 | 2/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | TGM2 | P21980 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL851946 | 0.88 | LMNA (0.52) | LMNASMN1; SMN2HTTSYKL3MBTL1 | |
| SCHEMBL851947 | 0.88 | LMNA (0.52) | LMNASMN1; SMN2HTTSYKL3MBTL1 | |
| SCHEMBL3951860 | 0.81 | LMNA (0.58) | LMNASMN1; SMN2HTTL3MBTL1MAPT | |
| SCHEMBL28392402 | 0.78 | LMNA (0.55) | LMNASMN1; SMN2HTTL3MBTL1MAPT | |
| SCHEMBL28392401 | 0.78 | LMNA (0.55) | LMNASMN1; SMN2HTTL3MBTL1MAPT | |
| SCHEMBL28221031 | 0.77 | LMNA (0.53) | LMNASMN1; SMN2HTTL3MBTL1MAPT | |
| SCHEMBL27696907 | 0.76 | CTSS (0.57) | SYKMAPTCTSLCTSSCTSB | |
| SCHEMBL16409736 | 0.75 | SMN1; SMN2 (0.57) | LMNASMN1; SMN2HTTSYKL3MBTL1 | |
| SCHEMBL5408118 | 0.75 | LMNA (0.60) | LMNASMN1; SMN2HTTSYKL3MBTL1 | |
| SCHEMBL22987362 | 0.75 | LMNA (0.53) | LMNASMN1; SMN2HTTSYKL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3564240-A1 | PIPERIDINE INTERMEDIATES | Purdue Pharma L.P. (US) | 2019-11-06 | — | — | EP | disclosed |