Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | SYK | P43405 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | TGM2 | P21980 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6514567 | 0.90 | SYK (0.56) | LMNASMN1; SMN2SYKMAPTHTT | |
| SCHEMBL6514568 | 0.90 | SYK (0.56) | LMNASMN1; SMN2SYKMAPTHTT | |
| Hydrochloric Acid SCHEMBL6512895 | 0.89 | SYK (0.55) | LMNASMN1; SMN2SYKMAPTHTT | |
| Hydrochloric Acid SCHEMBL6512903 | 0.89 | SYK (0.55) | LMNASMN1; SMN2SYKMAPTHTT | |
| SCHEMBL28650274 | 0.88 | LMNA (0.51) | LMNASMN1; SMN2SYKMAPTHTT | |
| SCHEMBL12347932 | 0.88 | LMNA (0.51) | LMNASMN1; SMN2SYKMAPTHTT | |
| SCHEMBL28221516 | 0.87 | LMNA (0.58) | LMNASMN1; SMN2MAPTHTTL3MBTL1 | |
| SCHEMBL28221005 | 0.87 | LMNA (0.58) | LMNASMN1; SMN2MAPTHTTL3MBTL1 | |
| SCHEMBL28221007 | 0.87 | LMNA (0.58) | LMNASMN1; SMN2MAPTHTTL3MBTL1 | |
| SCHEMBL2438788 | 0.86 | LMNA (0.52) | LMNASMN1; SMN2SYKMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3778601-A1 | CYTOTOXIC BENZODIAZEPINE DERIVATIVES | ImmunoGen, Inc. (US) | 2021-02-17 | — | — | EP | disclosed |