Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.41 |
| ▸ | MC4R | P32245 | 3/20 | 0.36 |
| ▸ | MC5R | P33032 | 3/20 | 0.36 |
| ▸ | MC3R | P41968 | 3/20 | 0.36 |
| ▸ | PYGL | P06737 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30296278 | 0.84 | ALOX5 (0.41) | ALOX5L3MBTL1EPHX1MEN1KMT2A | |
| SCHEMBL2497168 | 0.84 | ALOX5 (0.41) | ALOX5PYGLL3MBTL1EPHX1MEN1 | |
| SCHEMBL27971919 | 0.82 | ADH1A (0.47) | ALOX5L3MBTL1SLC6A2SLC6A4MEN1 | |
| SCHEMBL1953627 | 0.81 | ALOX5 (0.45) | ALOX5L3MBTL1EPHX1 | |
| Hydrochloric Acid SCHEMBL27529969 | 0.81 | ADH1A (0.46) | ALOX5L3MBTL1SLC6A2SLC6A4MEN1 | |
| SCHEMBL21197527 | 0.81 | ALOX5 (0.39) | ALOX5PYGLL3MBTL1MEN1KMT2A | |
| SCHEMBL2668588 | 0.81 | ALOX5 (0.47) | ALOX5EPHX1 | |
| SCHEMBL3920488 | 0.81 | ALOX5 (0.43) | ALOX5L3MBTL1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL21198740 | 0.79 | ALOX5 (0.38) | ALOX5PYGLL3MBTL1MEN1KMT2A | |
| SCHEMBL9071877 | 0.79 | L3MBTL1 (0.41) | ALOX5PYGLL3MBTL1EPHX1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3564253-A1 | ANTIDEPRESSANT COMPOUND AND PREPARATION METHOD AND APPLICATION THEREOF | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2019-11-06 | — | — | EP | disclosed |