SCHEMBL21549320

SCHEMBL21549320

CCCC[C@@H](Cc1ccc(-c2ccc(C(F)(F)F)cc2)cc1)NC(=O)OC(C)(C)C

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ MMP2 P08253 1/20 0.46
▸ MMP3 P08254 1/20 0.46
▸ PPARG P37231 3/20 0.46
▸ PPARA Q07869 3/20 0.46
▸ ATM Q13315 1/20 0.46
▸ CTSK P43235 11/20 0.44
▸ CTSS P25774 2/20 0.44
▸ FFAR2 O15552 1/20 0.44
▸ PPARD Q03181 1/20 0.41
▸ MME P08473 1/20 0.39
▸ ACE P12821 1/20 0.39
▸ CPA1 P15085 1/20 0.39
▸ ACE2 Q9BYF1 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21549384 0.89 PPARG (0.49) MMP2MMP3PPARGPPARAATM
SCHEMBL21528815 0.85 MMP2 (0.50) MMP2MMP3PPARGPPARAFFAR2
SCHEMBL14430204 0.85 ATM (0.50) PPARGPPARAATMCTSKCTSS
SCHEMBL4659427 0.85 ATM (0.50) PPARGPPARAATMCTSKCTSS
SCHEMBL21528813 0.85 MMP2 (0.50) MMP2MMP3PPARGPPARAFFAR2
SCHEMBL13970938 0.84 PPARG (0.49) PPARGPPARAATMCTSKCTSS
SCHEMBL12766379 0.84 PPARG (0.49) PPARGPPARAATMCTSKCTSS
SCHEMBL1519701 0.83 ATM (0.51) PPARGPPARAATMCTSKCTSS
SCHEMBL1595057 0.82 ATM (0.52) PPARGPPARAATMCTSKCTSS
SCHEMBL28800338 0.82 ATM (0.65) ATMCTSKCTSSACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11384060-B2 Amide compounds and use thereof ALPHALA CO., LTD. (TW) 2022-07-12 — — US disclosed
US-11384060-B2 Amide compounds and use thereof ALPHALA CO., LTD. (TW) 2022-07-12 — — US disclosed
US-20190337915-A1 AMIDE COMPOUNDS AND USE THEREOF ALPHALA CO., LTD. (TW) 2019-11-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190337915-A1 AMIDE COMPOUNDS AND USE THEREOF GLP1R, IAPP, GPR119 MMP2 2087/4885MMP3 3257/4885PPARG 93/4885
US-11384060-B2 Amide compounds and use thereof GLP1R, IAPP, GPR119 MMP2 2087/4885MMP3 3257/4885PPARG 93/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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