SCHEMBL2155017

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14726188	0.92	ABCG2 (0.49)	ABCG2ABCB1MAPTCYP19A1CYP17A1
	SCHEMBL2154805	0.90	CYP17A1 (0.58)	ABCG2ABCB1MAPTCYP19A1CYP17A1
	SCHEMBL14475576	0.87	CYP1A2 (0.62)	ABCG2ABCB1MAPTCYP19A1CYP17A1
	SCHEMBL14726166	0.86	PDE5A (0.50)	MAPTCYP19A1CYP17A1CYP11B2CYP11B1
	SCHEMBL14727934	0.86	ABCG2 (0.61)	ABCG2ABCB1MAPTCYP19A1CYP17A1
	SCHEMBL2154752	0.86	ABCG2 (0.56)	ABCG2ABCB1MAPTCYP19A1CYP17A1
	SCHEMBL20273715	0.84	ABCG2 (0.57)	ABCG2ABCB1MAPTCYP19A1CYP17A1
	SCHEMBL2154983	0.84	ABCG2 (0.65)	ABCG2ABCB1MAPTCYP19A1CYP3A4
	SCHEMBL14475594	0.84	CYP1A2 (0.64)	ABCG2ABCB1MAPTCYP19A1CYP17A1
	SCHEMBL14475151	0.83	ABCG2 (0.53)	ABCG2ABCB1MAPTCYP19A1CYP17A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.