SCHEMBL2154805

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2155017	0.90	ABCG2 (0.56)	CYP17A1CYP11B2CYP11B1CYP3A4ABCG2
	SCHEMBL29589455	0.90	CYP11B2 (0.55)	CYP17A1CYP11B2CYP11B1CYP3A4ABCG2
	SCHEMBL16183307	0.90	CYP11B2 (0.55)	CYP17A1CYP11B2CYP11B1CYP3A4ABCG2
	SCHEMBL14726188	0.87	ABCG2 (0.49)	CYP17A1CYP11B2CYP11B1CYP3A4ABCG2
	SCHEMBL2154780	0.86	CYP11B1 (0.56)	CYP17A1CYP11B2CYP11B1CYP3A4ABCG2
	SCHEMBL26857407	0.86	MEN1 (0.55)	CYP3A4ABCG2MAPTMEN1KMT2A
	SCHEMBL20273439	0.86	ABCG2 (0.57)	CYP17A1CYP11B2CYP11B1CYP3A4ABCG2
	SCHEMBL2154551	0.85	ABCG2 (0.56)	CYP17A1CYP11B2CYP11B1CYP3A4ABCG2
	SCHEMBL14474404	0.85	ABCG2 (0.62)	CYP17A1CYP11B2CYP11B1CYP3A4ABCG2
	SCHEMBL2154644	0.85	ABCG2 (0.56)	CYP17A1CYP11B2CYP11B1CYP3A4ABCG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.