SCHEMBL21551089

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29725214	1.00	KDM4E (0.42)	KDM4ETDP1MC4RHRH4LMNA
	SCHEMBL18390901	0.82	KDM4E (0.44)	KDM4ETDP1MC4RHRH4LMNA
	SCHEMBL16333045	0.79	MC4R (0.44)	KDM4ETDP1MC4RHRH4LMNA
	SCHEMBL5133063	0.79	LMNA (0.46)	KDM4EMC4RHRH4LMNALTA4H
	SCHEMBL31002170	0.79	CXCR4 (0.50)	KDM4EGAAHRH3
	SCHEMBL2933048	0.78	KDM4E (0.45)	KDM4ETDP1MC4RHRH4LMNA
	SCHEMBL31002439	0.77	HRH3 (0.35)	LMNAAURKBGAAHRH3
	SCHEMBL2930850	0.75	TRPV6 (0.53)	KDM4ETDP1MC4RLMNACHKA
	SCHEMBL5133060	0.74	HRH3 (0.48)	KDM4EMC4RLMNAHRH3HDAC6
	SCHEMBL16615296	0.74	TNKS (0.47)	KDM4EMC4RHRH4LMNALTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.