SCHEMBL215519

SCHEMBL215519

CC(CCc1ccccc1)N=C=O

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.45
POLB P06746 1/20 0.44
ALDH1A1 P00352 3/20 0.42
SMN1; SMN2 Q16637 3/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
HTT P42858 1/20 0.42
HPGD P15428 1/20 0.42
OPRK1 P41145 1/20 0.41
SIGMAR1 Q99720 2/20 0.41
KDM4E B2RXH2 1/20 0.41
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4090888 0.87 MEN1 (0.37) TSHRPOLBMEN1KMT2AOPRK1
SCHEMBL25306116 0.85 BCHE (0.56) SIGMAR1
SCHEMBL1934349 0.81 CNR2 (0.43) TSHRPOLBALDH1A1SMN1; SMN2MEN1
SCHEMBL2729032 0.81 SLC6A2 (0.48) TSHRMEN1KMT2ACYP1A2HPGD
SCHEMBL27515553 0.81 SLC6A2 (0.48) TSHRMEN1KMT2ACYP1A2HPGD
SCHEMBL21056125 0.81 SLC6A2 (0.48) TSHRMEN1KMT2ACYP1A2HPGD
SCHEMBL11760662 0.81 CYP3A4 (0.52) TSHRALDH1A1SMN1; SMN2MEN1KMT2A
SCHEMBL25305851 0.80 HTT (0.54) POLBALDH1A1SMN1; SMN2MEN1KMT2A
SCHEMBL153435 0.79 GABRA1 (0.37) TSHRALDH1A1SMN1; SMN2MEN1KMT2A
SCHEMBL29115701 0.79 CTSC (0.40) TSHRPOLBALDH1A1SMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12509419-B2 Process for the distillation of isocyanates COVESTRO DEUTSCHLAND AG (DE) 2025-12-30 US claimed
EP-1717223-B2 Method for the purification of isocyanates BASF SE (DE) 2023-01-04 EP claimed
US-20220380303-A1 PROCESS FOR THE DISTILLATION OF ISOCYANATES COVESTRO DEUTSCHLAND AG (DE) 2022-12-01 US claimed
EP-4038049-A1 PROCESS FOR THE DISTILLATION OF ISOCYANATES Covestro Intellectual Property GmbH & Co. KG (DE) 2022-08-10 EP claimed
CN-114423736-A Method for distilling isocyanates 科思创知识产权两合公司 2022-04-29 CN claimed
WO-2021063760-A1 PROCESS FOR THE DISTILLATION OF ISOCYANATES COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) 2021-04-08 WO claimed
EP-3798208-A1 METHOD FOR DISTILLATION OF ISOCYANATES Covestro Deutschland AG (DE) 2021-03-31 EP claimed
EP-1717223-B1 Method for the purification of isocyanates BASF SE (DE) 2016-07-20 EP claimed
US-8088944-B2 Method for the purification of isocyanates BASF SE (DE) 2012-01-03 US claimed
CN-1982292-B Method for the purification of isocyanates BASF AG 2011-09-07 CN claimed
CN-1982292-A Method for the purification of isocyanates BASF AG (DE) 2007-06-20 CN claimed
US-20070015934-A1 Method for the purification of isocyanates BASF AKTIENGESELLSCHAFT (DE) 2007-01-18 US claimed
EP-1717223-A2 Method for the purification of isocyanates BASF Aktiengesellschaft (DE) 2006-11-02 EP claimed
US-12509419-B2 Process for the distillation of isocyanates COVESTRO DEUTSCHLAND AG (DE) 2025-12-30 US disclosed
CN-114423736-B Method for distilling isocyanates 科思创德国股份有限公司 2025-02-18 CN disclosed
EP-1717223-B2 Method for the purification of isocyanates BASF SE (DE) 2023-01-04 EP disclosed
US-5516749-A Herbicidal and fungicidal substituted triazolinones BAYER AKTIENGESELLSCHAFT (DE) 1996-05-14 US disclosed
US-5276008-A Herbicides and plant growth regulators BAYER AKTIENGESELLSCHAFT (DE) 1994-01-04 US disclosed
EP-0505819-A1 Substituted triazolinones BAYER AG (DE) 1992-09-30 EP disclosed
EP-0502307-A2 Substituted 4,5-diamino-1,2,4-triazol-3-(thi)ones BAYER AG (DE) 1992-09-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12509419-B2 Process for the distillation of isocyanates ACMSD, MRPL9, CA9 TSHR 4417/4885POLB 2018/4885ALDH1A1 3110/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.