Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL153435 | 0.88 | GABRA1 (0.37) | MEN1KMT2AACHETAAR1GABRA1 | |
| SCHEMBL215519 | 0.87 | TSHR (0.45) | MEN1KMT2ATSHROPRK1POLB | |
| SCHEMBL11545579 | 0.83 | MEN1 (0.48) | MEN1KMT2AAOC3 | |
| SCHEMBL23121590 | 0.81 | PNMT (0.43) | ACHETAAR1TSHROPRK1PNMT | |
| SCHEMBL635206 | 0.81 | PNMT (0.43) | ACHETAAR1TSHROPRK1PNMT | |
| SCHEMBL11760662 | 0.76 | CYP3A4 (0.52) | MEN1KMT2AGABRA1GABRB2TSHR | |
| SCHEMBL25305851 | 0.75 | HTT (0.54) | MEN1KMT2ATAAR1AOC3POLB | |
| SCHEMBL25306116 | 0.75 | BCHE (0.56) | — | |
| SCHEMBL27540165 | 0.73 | CYP3A4 (0.41) | GABRA1GABRB2 | |
| SCHEMBL9579004 | 0.72 | OPRM1 (0.50) | MEN1KMT2ATAAR1GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7504459-B2 | Methacrylate amide acetals in coatings | E.I. DU PONT DE NEMOURS & COMPANY (US) | 2009-03-17 | — | — | US | disclosed |