Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 8/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | MLNR | O43193 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL546245 | 0.87 | PDK2 (0.39) | PDK2HTR2AMLNRNR1I2CHRM2 | |
| SCHEMBL23040369 | 0.87 | ESR1 (0.37) | PDK2HTR2AMLNRNR1I2CHRM2 | |
| SCHEMBL30318820 | 0.87 | ESR1 (0.37) | PDK2HTR2AMLNRNR1I2CHRM2 | |
| SCHEMBL20932322 | 0.85 | ESR1 (0.39) | PDK2HTR2AMLNRNR1I2CHRM2 | |
| SCHEMBL22920726 | 0.85 | PGR (0.38) | PDK2HTR2AMLNRNR1I2CHRM2 | |
| SCHEMBL20615981 | 0.85 | MEN1 (0.38) | PDK2HTR2AMLNRNR1I2CHRM2 | |
| SCHEMBL23076421 | 0.85 | ALDH1A1 (0.35) | PDK2HTR2AMLNRNR1I2CHRM2 | |
| SCHEMBL23040362 | 0.85 | PGR (0.38) | PDK2HTR2AMLNRNR1I2CHRM2 | |
| SCHEMBL24730433 | 0.85 | PGR (0.38) | PDK2HTR2AMLNRNR1I2CHRM2 | |
| SCHEMBL23870792 | 0.85 | PDK2 (0.35) | PDK2HTR2AMLNRNR1I2CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230139809-A1 | BENZIMIDAZOLE DERIVATIVES | MERCK PATENT GMBH (DE) | 2023-05-04 | — | — | US | disclosed |
| US-20230139809-A1 | BENZIMIDAZOLE DERIVATIVES | MERCK PATENT GMBH (DE) | 2023-05-04 | — | — | US | disclosed |
| WO-2021151922-A1 | BENZIMIDAZOLE DERIVATIVES | MERCK PATENT GMBH (DE) | 2021-08-05 | — | — | WO | disclosed |
| WO-2019216600-A1 | NOVEL OXIME ESTER COMPOUND AND PHOTORESIST COMPOSITION COMPRISING SAME | 주식회사 트리엘 (KR) | 2019-11-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230139809-A1 | BENZIMIDAZOLE DERIVATIVES | ECI1, COX4I1, BRD4 | PDK2 275/4885HTR2A 3025/4885MLNR 2619/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.