Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | RHEB | Q15382 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21568003 | 0.99 | HPGD (0.55) | HPGDSMN1; SMN2KMT2AALDH1A1CYP1A2 | |
| SCHEMBL21551949 | 0.85 | SMN1; SMN2 (0.58) | HPGDSMN1; SMN2KMT2AALDH1A1CYP1A2 | |
| SCHEMBL21551921 | 0.79 | HDAC1 (0.57) | HPGDSMN1; SMN2ALDH1A1CYP1A2ALOX5 | |
| SCHEMBL21568019 | 0.79 | ALDH1A1 (0.56) | HPGDSMN1; SMN2KMT2AALDH1A1CYP1A2 | |
| SCHEMBL22708463 | 0.78 | ALDH1A1 (0.57) | HPGDSMN1; SMN2KMT2AALDH1A1ALOX5 | |
| SCHEMBL21551943 | 0.78 | ALDH1A1 (0.51) | HPGDSMN1; SMN2KMT2AALDH1A1CYP1A2 | |
| SCHEMBL16380446 | 0.77 | TMEM97 (0.65) | HPGDSMN1; SMN2KMT2AALDH1A1CYP1A2 | |
| SCHEMBL21552087 | 0.76 | MCHR1 (0.54) | HPGDALDH1A1ALOX5TMEM97SIGMAR1 | |
| Hydrochloric Acid SCHEMBL27761670 | 0.76 | TMEM97 (0.63) | HPGDSMN1; SMN2KMT2AALDH1A1CYP1A2 | |
| SCHEMBL6642558 | 0.76 | ALDH1A1 (0.55) | HPGDSMN1; SMN2KMT2AALDH1A1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019216810-A1 | NEW ANTIFUNGAL COMPOUNDS | URBAN CONSTANTIN (SE) | 2019-11-14 | — | — | WO | claimed |
| WO-2019216810-A1 | NEW ANTIFUNGAL COMPOUNDS | URBAN CONSTANTIN (SE) | 2019-11-14 | — | — | WO | disclosed |