Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | THRA | P10827 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.46 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21551921 | 0.87 | HDAC1 (0.57) | ALDH1A1SETD7HPGDALOX5SMN1; SMN2 | |
| SCHEMBL6642558 | 0.85 | ALDH1A1 (0.55) | ALDH1A1SETD7HPGDALOX5SMN1; SMN2 | |
| SCHEMBL6642553 | 0.85 | ALDH1A1 (0.55) | ALDH1A1SETD7HPGDALOX5SMN1; SMN2 | |
| SCHEMBL30046741 | 0.85 | ALDH1A1 (0.73) | ALDH1A1SETD7HPGDALOX5SMN1; SMN2 | |
| SCHEMBL4495601 | 0.84 | ALDH1A1 (0.60) | ALDH1A1SETD7HPGDALOX5SMN1; SMN2 | |
| SCHEMBL22708464 | 0.83 | ALDH1A1 (0.58) | ALDH1A1SETD7HPGDALOX5SMN1; SMN2 | |
| SCHEMBL21568019 | 0.83 | ALDH1A1 (0.56) | ALDH1A1SETD7HPGDALOX5SMN1; SMN2 | |
| SCHEMBL6641126 | 0.83 | ALDH1A1 (0.56) | ALDH1A1SETD7HPGDALOX5SMN1; SMN2 | |
| SCHEMBL6641130 | 0.83 | ALDH1A1 (0.56) | ALDH1A1SETD7HPGDALOX5SMN1; SMN2 | |
| SCHEMBL21552087 | 0.83 | MCHR1 (0.54) | ALDH1A1SETD7HPGDALOX5NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11396505-B2 | Inhibitors of CaMKK2 and uses of same | NEW YORK UNIVERSITY (US) | 2022-07-26 | — | — | US | disclosed |
| US-20200369656-A1 | INHIBITORS OF CAMKK2 AND USES OF SAME | NEW YORK UNIVERSITY | 2020-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11396505-B2 | Inhibitors of CaMKK2 and uses of same | CAMKK2, CAMKK1, CAMK1 | ALDH1A1 4136/4885SETD7 4180/4885HPGD 1168/4885 |
| US-20200369656-A1 | INHIBITORS OF CAMKK2 AND USES OF SAME | CAMKK2, CAMKK1, CAMK1 | ALDH1A1 4136/4885SETD7 4180/4885HPGD 1168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.