Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21568003 | 0.86 | HPGD (0.55) | SMN1; SMN2KMT2AHPGDHRH4HRH3 | |
| Methane SCHEMBL21551969 | 0.85 | HPGD (0.54) | SMN1; SMN2KMT2AHPGDHRH4HRH3 | |
| SCHEMBL16380446 | 0.79 | TMEM97 (0.65) | SMN1; SMN2KMT2AHPGDALDH1A1MEN1 | |
| SCHEMBL21551953 | 0.79 | CYP1A2 (0.50) | SMN1; SMN2KMT2AHPGDALDH1A1MAPT | |
| SCHEMBL21551921 | 0.79 | HDAC1 (0.57) | SMN1; SMN2HPGDALDH1A1MAPTPOLB | |
| SCHEMBL21568402 | 0.78 | ALDH1A1 (0.52) | SMN1; SMN2KMT2AALDH1A1MAPTPOLB | |
| Hydrochloric Acid SCHEMBL27761670 | 0.78 | TMEM97 (0.63) | SMN1; SMN2KMT2AHPGDALDH1A1MEN1 | |
| SCHEMBL21552169 | 0.78 | ALDH1A1 (0.63) | KMT2AHPGDALDH1A1POLBMEN1 | |
| SCHEMBL21568019 | 0.78 | ALDH1A1 (0.56) | SMN1; SMN2KMT2AHPGDALDH1A1MAPT | |
| SCHEMBL22708463 | 0.77 | ALDH1A1 (0.57) | SMN1; SMN2KMT2AHPGDALDH1A1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019216810-A1 | NEW ANTIFUNGAL COMPOUNDS | URBAN CONSTANTIN (SE) | 2019-11-14 | — | — | WO | claimed |
| WO-2019216810-A1 | NEW ANTIFUNGAL COMPOUNDS | URBAN CONSTANTIN (SE) | 2019-11-14 | — | — | WO | disclosed |
| WO-2019216810-A1 | NEW ANTIFUNGAL COMPOUNDS | URBAN CONSTANTIN (SE) | 2019-11-14 | — | — | WO | disclosed |