SCHEMBL2155205

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14474095	0.88	CLK4 (0.49)	CYP11B2CYP11B1CYP19A1CYP17A1CYP1A2
	SCHEMBL2154742	0.84	CYP11B2 (0.56)	CYP11B2CYP11B1CYP19A1CYP17A1NPC1
	SCHEMBL2154578	0.84	CYP11B2 (0.56)	CYP11B2CYP11B1CYP19A1CYP17A1NPC1
	SCHEMBL2154983	0.81	ABCG2 (0.65)	CYP19A1CYP1A2CYP3A4CYP2D6CYP2C9
	SCHEMBL16183290	0.81	CLK4 (0.59)	CYP11B2CYP11B1CYP19A1CYP17A1NPC1
	SCHEMBL14475040	0.81	ABCG2 (0.48)	CYP11B2CYP11B1CYP19A1CYP17A1NPC1
	SCHEMBL16183291	0.79	GBA1 (0.53)	CYP11B2CYP11B1CYP19A1CYP17A1NPC1
	SCHEMBL14727500	0.79	ABCG2 (0.62)	CYP11B2CYP11B1CYP19A1CYP17A1NPC1
	SCHEMBL14731305	0.78	NPC1 (0.54)	CYP11B2CYP11B1CYP19A1CYP17A1NPC1
	SCHEMBL2162552	0.77	NPC1 (0.53)	CYP11B2CYP11B1CYP19A1CYP17A1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.