Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL151528 | 0.90 | IDO1 (0.40) | KDM4EALDH1A1KMT2AMAPTMEN1 | |
| Phosphoric Acid SCHEMBL6338665 | 0.78 | ALDH1A1 (0.49) | KDM4EALDH1A1KMT2AMAPTMEN1 | |
| Phosphoric Acid SCHEMBL5664380 | 0.78 | KDM4E (0.37) | KDM4EALDH1A1KMT2AMAPTMEN1 | |
| Phosphoric Acid SCHEMBL7800036 | 0.76 | HPGD (0.39) | ALDH1A1MAPTHTTIDO1LMNA | |
| SCHEMBL272098 | 0.71 | KDM4E (0.35) | KDM4EALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL28287733 | 0.70 | BAZ2B (0.38) | KDM4EALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL20574565 | 0.70 | KDM4E (0.33) | KDM4EALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL28852179 | 0.70 | IDO1 (0.40) | KDM4EALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL2246479 | 0.69 | KDM4E (0.32) | KDM4ESMN1; SMN2LMNA | |
| SCHEMBL28024648 | 0.68 | AKR1C3 (0.49) | KDM4EALDH1A1KMT2AMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10379015-B2 | Method for labeling concentration density differentials of an analyte in a biological sample | DIAGNOSTIC BIOSYSTEMS (US) | 2019-08-13 | — | — | US | claimed |
| US-20180348099-A1 | METHOD FOR LABELING CONCENTRATION DENSITY DIFFERENTIALS OF AN ANALYTE IN A BIOLOGICAL SAMPLE | DIAGNOSTIC BIOSYSTEMS (US) | 2018-12-06 | — | — | US | claimed |
| EP-2519645-B1 | A culture medium for screening or enrichment of methicillin-resistant S. aureus | BIO RAD INNOVATIONS (FR) | 2018-08-22 | — | — | EP | claimed |
| US-9434978-B2 | Culture medium for screening or enrichment of methicillin-resistant S. aureus | BIO-RAD INNOVATIONS (FR) | 2016-09-06 | — | — | US | claimed |
| US-20120322098-A1 | CULTURE MEDIUM FOR SCREENING OR ENRICHMENT OF METHICILLIN-RESISTANT S. AUREUS | BIO-RAD INNOVATIONS (FR) | 2012-12-20 | — | — | US | claimed |
| EP-2519645-A1 | A CULTURE MEDIUM FOR SCREENING OR ENRICHMENT OF METHICILLIN-RESISTANT S. AUREUS | Bio-Rad Innovations (FR) | 2012-11-07 | — | — | EP | claimed |
| WO-2011080305-A1 | A CULTURE MEDIUM FOR SCREENING OR ENRICHMENT OF METHICILLIN-RESISTANT S. AUREUS | BIO-RAD PASTEUR (FR) | 2011-07-07 | — | — | WO | claimed |
| EP-0922112-A4 | FORMAZAN-BASED IMMUNOASSAY | KIRKEGAARD & PERRY LAB INC (US) | 2000-07-12 | — | — | EP | claimed |
| EP-0922112-A1 | FORMAZAN-BASED IMMUNOASSAY | Kirkegaard & Perry Laboratories, Inc. (US) | 1999-06-16 | — | — | EP | claimed |
| WO-1997042342-A1 | FORMAZAN-BASED IMMUNOASSAY | KIRKEGAARD & PERRY LABORATORIES, INC. (US) | 1997-11-13 | — | — | WO | claimed |
| WO-1992021974-A1 | STABLE ALKALINE PHOSPHATASE COMPOSITIONS WITH COLOR ENHANCEMENT AND THEIR USE IN ASSAYS | QUIDEL CORPORATION (US) | 1992-12-10 | — | — | WO | claimed |
| US-10379015-B2 | Method for labeling concentration density differentials of an analyte in a biological sample | DIAGNOSTIC BIOSYSTEMS (US) | 2019-08-13 | — | — | US | disclosed |
| US-20180348099-A1 | METHOD FOR LABELING CONCENTRATION DENSITY DIFFERENTIALS OF AN ANALYTE IN A BIOLOGICAL SAMPLE | DIAGNOSTIC BIOSYSTEMS (US) | 2018-12-06 | — | — | US | disclosed |
| EP-2519645-B1 | A culture medium for screening or enrichment of methicillin-resistant S. aureus | BIO RAD INNOVATIONS (FR) | 2018-08-22 | — | — | EP | disclosed |
| US-9434978-B2 | Culture medium for screening or enrichment of methicillin-resistant S. aureus | BIO-RAD INNOVATIONS (FR) | 2016-09-06 | — | — | US | disclosed |
| US-20120322098-A1 | CULTURE MEDIUM FOR SCREENING OR ENRICHMENT OF METHICILLIN-RESISTANT S. AUREUS | BIO-RAD INNOVATIONS (FR) | 2012-12-20 | — | — | US | disclosed |
| EP-2519645-A1 | A CULTURE MEDIUM FOR SCREENING OR ENRICHMENT OF METHICILLIN-RESISTANT S. AUREUS | Bio-Rad Innovations (FR) | 2012-11-07 | — | — | EP | disclosed |
| WO-2011080305-A1 | A CULTURE MEDIUM FOR SCREENING OR ENRICHMENT OF METHICILLIN-RESISTANT S. AUREUS | BIO-RAD PASTEUR (FR) | 2011-07-07 | — | — | WO | disclosed |