SCHEMBL21553765

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29725208	1.00	HRH4 (0.49)	HRH4MC4RLMNACHKACA2
	SCHEMBL3051997	0.82	HRH3 (0.43)	ALDH1A1KDM4ETDP1MEN1KMT2A
	Hydrochloric Acid SCHEMBL27808142	0.81	HRH3 (0.42)	ALDH1A1KDM4ETDP1MEN1KMT2A
	SCHEMBL21550463	0.79	CXCR4 (0.54)	ALDH1A1NPC1RAB9AMEN1KMT2A
	SCHEMBL20324223	0.78	HRH4 (0.44)	HRH4MC4RLMNACHKACA2
	SCHEMBL22971419	0.77	ALDH1A1 (0.38)	ALDH1A1
	SCHEMBL20332370	0.76	PARP1 (0.39)	ALDH1A1
	SCHEMBL30948016	0.76	ALDH1A1 (0.45)	ALDH1A1KDM4ETP53MEN1KMT2A
	SCHEMBL31416748	0.75	PDCD1LG2 (0.45)	ALDH1A1KDM4ENPC1RAB9AMEN1
	SCHEMBL17331651	0.75	HTR3E (0.54)	HRH4MC4RLMNACHKACA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.