Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.45 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.45 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.36 |
| ▸ | TRPV6 | Q9H1D0 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30948016 | 0.84 | ALDH1A1 (0.45) | TRPV6ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL21550463 | 0.79 | CXCR4 (0.54) | ALDH1A1TSHRMEN1KMT2ACXCR4 | |
| SCHEMBL21553765 | 0.75 | HRH4 (0.49) | ALDH1A1MEN1KMT2AKDM4EHRH3 | |
| SCHEMBL29725208 | 0.75 | HRH4 (0.49) | ALDH1A1MEN1KMT2AKDM4EHRH3 | |
| SCHEMBL30309949 | 0.72 | SIGMAR1 (0.62) | TRPV6TSHR | |
| SCHEMBL3051997 | 0.72 | HRH3 (0.43) | ALDH1A1MEN1KMT2AKDM4EHRH3 | |
| Hydrochloric Acid SCHEMBL27808142 | 0.71 | HRH3 (0.42) | ALDH1A1MEN1KMT2AKDM4EHRH3 | |
| SCHEMBL20332370 | 0.70 | PARP1 (0.39) | ALDH1A1 | |
| SCHEMBL31416797 | 0.69 | MCHR1 (0.36) | PDCD1LG2CD274SOS1TRPV6 | |
| SCHEMBL31416707 | 0.69 | ALDH1A1 (0.40) | PDCD1LG2CD274ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4746964-A1 | NEW PYRAZOLOPYRIDINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2026-05-27 | — | — | EP | disclosed |
| WO-2025017078-A1 | NEW PYRAZOLOPYRIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-01-23 | — | — | WO | disclosed |