SCHEMBL21553864

SCHEMBL21553864

CNC(CCC(=O)O)c1nccs1

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CTSA P10619 15/20 0.39
ANPEP P15144 1/20 0.37
ENPEP Q07075 1/20 0.37
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21552487 0.84 CTSA (0.47) CTSA
SCHEMBL10862235 0.76 CTSA (0.42) CTSA
SCHEMBL13075752 0.75 CYP19A1 (0.40)
SCHEMBL21552119 0.73 CTSA (0.45) CTSA
SCHEMBL27787271 0.72 ALDH1A1 (0.40) CTSA
SCHEMBL21552311 0.71 NR3C1 (0.41) CTSA
SCHEMBL19257958 0.71 PTPRB (0.47) CTSACYP2D6CYP2C19
SCHEMBL28622173 0.70 ALDH1A1 (0.46) CYP1A2CYP3A4CYP2C19
SCHEMBL21525583 0.69 CTSA (0.50) CTSA
SCHEMBL10669573 0.69 CTSA (0.49) CTSA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019216742-A1 NOVEL COMPOUND EXHIBITING ENTEROPEPTIDASE INHIBITORY ACTIVITY 주식회사 엘지화학 (KR) 2019-11-14 WO disclosed