Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HINT1 | P49773 | 1/20 | 0.56 |
| ▸ | HLCS | P50747 | 3/20 | 0.51 |
| ▸ | DOT1L | Q8TEK3 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21528351 | 0.97 | HINT1 (0.55) | HINT1HLCSDOT1L | |
| SCHEMBL21553923 | 0.96 | HINT1 (0.59) | HINT1HLCS | |
| SCHEMBL18130974 | 0.87 | HINT1 (0.53) | HINT1HLCS | |
| SCHEMBL21553924 | 0.87 | HINT1 (0.49) | HINT1HLCS | |
| SCHEMBL21553888 | 0.86 | HINT1 (0.49) | HINT1HLCSDOT1L | |
| SCHEMBL21528356 | 0.83 | HINT1 (0.50) | HINT1HLCS | |
| SCHEMBL21553970 | 0.83 | DOT1L (0.58) | HINT1DOT1L | |
| SCHEMBL18137735 | 0.82 | DOT1L (0.53) | DOT1L | |
| SCHEMBL1101052 | 0.82 | HINT1 (0.63) | HINT1HLCS | |
| SCHEMBL21553884 | 0.80 | DOT1L (0.59) | HINT1DOT1L |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190339283-A1 | BIOCONJUGATES OF HETEROCYCLIC COMPOUNDS | HAO, XIUJUAN | 2019-11-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190339283-A1 | BIOCONJUGATES OF HETEROCYCLIC COMPOUNDS | AHCY, MMAB, ESD | HINT1 244/4885HLCS 59/4885DOT1L 2494/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.