Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 11/20 | 0.37 |
| ▸ | METAP2 | P50579 | 6/20 | 0.35 |
| ▸ | METAP1 | P53582 | 5/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
| ▸ | CTSC | P53634 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21554935 | 0.81 | REN (0.47) | RENMETAP2METAP1 | |
| Hydrochloric Acid SCHEMBL21526200 | 0.80 | REN (0.47) | RENMETAP2METAP1 | |
| Hydrochloric Acid SCHEMBL21526201 | 0.80 | REN (0.47) | RENMETAP2METAP1 | |
| Hydrochloric Acid SCHEMBL20474494 | 0.67 | BACE1 (0.46) | RENMETAP2METAP1CTSC | |
| Hydrochloric Acid SCHEMBL20474493 | 0.67 | BACE1 (0.46) | RENMETAP2METAP1CTSC | |
| SCHEMBL21554937 | 0.66 | TDP1 (0.44) | METAP2METAP1CTSC | |
| SCHEMBL21554938 | 0.66 | TDP1 (0.44) | METAP2METAP1CTSC | |
| SCHEMBL28519747 | 0.66 | TDP1 (0.44) | METAP2METAP1CTSC | |
| Hydrochloric Acid SCHEMBL21526212 | 0.65 | TDP1 (0.43) | METAP2METAP1CTSC | |
| Hydrochloric Acid SCHEMBL21526213 | 0.65 | TDP1 (0.43) | METAP2METAP1CTSC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3564211-A1 | DIPEPTIDYL KETOAMIDE META-METHOXYPHENYL DERIVATIVES AND USES THEREOF | LANDSTEINER GENMED, S.L. (ES) | 2019-11-06 | — | — | EP | disclosed |