Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | BACE1 | P56817 | 7/20 | 0.42 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | METAP1 | P53582 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | CTSD | P07339 | 4/20 | 0.41 |
| ▸ | BACE2 | Q9Y5Z0 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CTSC | P53634 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21554938 | 1.00 | TDP1 (0.44) | TDP1ALDH1A1BACE1METAP2METAP1 | |
| SCHEMBL28519747 | 1.00 | TDP1 (0.44) | TDP1ALDH1A1BACE1METAP2METAP1 | |
| Hydrochloric Acid SCHEMBL21526213 | 0.99 | TDP1 (0.43) | TDP1ALDH1A1BACE1METAP2METAP1 | |
| Hydrochloric Acid SCHEMBL21526212 | 0.99 | TDP1 (0.43) | TDP1ALDH1A1BACE1METAP2METAP1 | |
| SCHEMBL21554931 | 0.87 | CTSC (0.52) | TDP1ALDH1A1BACE1CTSDBACE2 | |
| SCHEMBL21526206 | 0.86 | ALDH1A1 (0.43) | TDP1ALDH1A1BACE1LTA4HCTSD | |
| SCHEMBL21526205 | 0.86 | ALDH1A1 (0.43) | TDP1ALDH1A1BACE1LTA4HCTSD | |
| SCHEMBL21012397 | 0.85 | SMN1; SMN2 (0.45) | TDP1ALDH1A1BACE1LTA4HCTSD | |
| SCHEMBL21555137 | 0.85 | SMN1; SMN2 (0.45) | TDP1ALDH1A1BACE1LTA4HCTSD | |
| SCHEMBL23921537 | 0.84 | LAP3 (0.46) | TDP1ALDH1A1BACE1CTSDBACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3788031-B1 | DIPEPTIDYL KETOAMIDE META-METHOXYPHENYL DERIVATIVES AND USES THEREOF | LANDSTEINER GENMED S L (ES) | 2023-09-27 | — | — | EP | disclosed |
| EP-3564211-A1 | DIPEPTIDYL KETOAMIDE META-METHOXYPHENYL DERIVATIVES AND USES THEREOF | LANDSTEINER GENMED, S.L. (ES) | 2019-11-06 | — | — | EP | disclosed |